“…The mean age of participants ranged from 55 to 68.4 years, and 44% to 77% of participants were men. Of these studies, 16 studies reported results by hepatic metastasis using as the unit of analysis,7, 11–13, 15, 16, 18, 19, 23, 25–29, 31, 33 14 studies by pelvic metastasis or local regional recurrence7, 8, 11–13, 15, 16, 18, 19, 23, 25, 27, 30, 31 and 19 studies by distant metastasis or whole body involvement 9–17, 19–27, 32…”