“…Since the production of the anti-DMPO antibody [23], a number of protein radicals have been detected by DMPO-based IST [21, 32], including myoglobin [23, 34–36], hemoglobin [22, 35, 37–38], cytochrome c [39], neuroglobin [40], Cu, Zn-superoxide dismutase (SOD1) [41–43] and Mn-SOD [44], catalase [33], myeloperoxidase [45–46], eosinophil peroxidase [47], lactoperoxidase [48–49], microglobulin [50], albumin [43, 51], thyroid peroxidase (TPO)[25], α-lactalbumin [52] and Ras GTPase [53]. Oxidants used to generate these radicals included H 2 O 2 , peroxynitrite, Cu 2+ /H 2 O 2 , hypochlorous acid, tert -butylhydroperoxide, peroxymonocarbonate, and reactive species generated from ketoprofen plus UV-A, riboflavin plus UV-A irradiation and nano-TiO 2 plus UV-A irradiation.…”