Detection of proteins and intact microorganisms using microfabricated flexural plate silicon resonator arrays

Pepper, Jane Wu; Noring, Richard; Klempner, Mark S.; Cunningham, Brian T.; Петрович, Амосов Александр; Bousquet, Robert R.; Clapp, Christopher; Brady, Jeanne M.; Hugh, Brenda

doi:10.1016/s0925-4005(03)00641-5

Cited by 33 publications

(17 citation statements)

References 17 publications

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“…In addition, the exclusive fingerprint is dearly useful for developing optical biosensors, in which a high degree of resolution, sensibility and biocompatibility are required. [7,8] Recently, porous silicon colloids with spherical shape have been successfully developed. [9,10] It has been found out that these PSi colloids have a unique PL spectrum in the near IR region, which depends on the colloid size and its porosity.…”

Section: Doi: 101002/adma201104490mentioning

confidence: 99%

Nanoporous Anodic Alumina Barcodes: Toward Smart Optical Biosensors

et al. 2012

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Section: Doi: 101002/adma201104490mentioning

confidence: 99%

Nanoporous Anodic Alumina Barcodes: Toward Smart Optical Biosensors

et al. 2012

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“…PL biosensors take advantage not only of the exclusive PL fingerprint of p-AAO but also of other interesting properties of p-AAO such as its thermal stability, environment-resisting and biodegradability. Biosensors based on p-AAO PL are characterized by their high degree of resolution, sensibility and biocompatibility [100,133]. Moreover, their performed measurements are reliable and reproducible as the PL spectrum of p-AAO remains stable over time [98].…”

Section: Photoluminescence-based Applications Of Porous Anodic Aluminmentioning

confidence: 99%

Optical Properties of Nanoporous Anodic Alumina and Derived Applications

et al. 2015

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Inexpensive formation of periodically ordered structures with periodicities and feature sizes lower than 100 nm has triggered a vast amount or research in recent years. Of particular interest in nanotechnology is the nanoporous alumina, which can be produced with a self-organized arrangement of pores in the adequate anodization conditions. Most of the interest of this material is based in its outstanding physical and chemical and properties, and more specifically in its optical properties. The interaction of light with the nanostructured porous alumina gives rise to a wealth of optical properties that have their interest both in research level and also in application. In this work we aim at giving an extensive review of the published research on the optical properties of nanoporous alumina. The review will account for the different studied optical properties of this material such as the existence of a photonic stop band originated from its quasi-random nanostructure, the interferometric and light guiding properties that can be applied to biosensing, the structure nanoengineering to achieve more complex photonic behaviour such as distributed-Bragg reflectors or rugate filters, and the photoluminescence properties. In a second part, a summary of the different applications proposed on the basis of these properties, such as in biotechnology or energy will be given. IntroductionAmong the different features and properties of porous anodic alumina (p-AAO), its optical properties are of special interest and have been the subject of very intensive research. The interaction of light with p-AAO can be analyzed from different points of view: the material interaction, the porous structure interaction or the relation of geometrical features of the nanostructure (periodicity or quasi-periodicity, distance

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“…In addition, Lamb-wavetyped sensors differ from the other two types in the configuration of the electrodes and the thickness of the medium that acoustic waves propagate in. They are typically made of a thin propagation plate (~2-μm to 7-μm thick piezoelectric membrane) supported on a substrate, with electrodes in interlocking comb shape, also known as interdigitated transducers (IDTs) [2] - [8]. This configuration results in high mass sensitivity [2], [7], [9] and strong electromechanical coupling [10], thus making lamb-wavetyped sensors a competitive candidate for sensing applications.…”

Section: Introductionmentioning

confidence: 99%

GaN-based lamb-wave mass-sensors on silicon substrates

et al. 2010

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Lamb-wave mass-sensors were fabricated with MOCVD-grown GaN-based thin films on silicon substrates. Crystalline GaN provides an alternative choice of material for fabricating Lamb-wave sensors. The advantageous properties of this material include high acoustic velocity, high chemical, mechanical and thermal stability, and the potential to integrate with a wide range of GaN-based devices such as high electron mobility transistor (HEMT) circuits, light emitting diodes (LED) and other photonic devices. We successfully developed GaNbased Lamb-wave mass-sensors in small size (membrane size of ~1mm × 1mm). The sensors showed good signal strength and mass sensitivity, comparable to other mass-sensors using conventional materials. This novel approach not only allows robust low-cost sensors to be fabricated, but also enables future integration with generic GaN-based devices on the same chip (i.e. lab-on-a-chip).I.

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Detection of proteins and intact microorganisms using microfabricated flexural plate silicon resonator arrays

Cited by 33 publications

References 17 publications

Nanoporous Anodic Alumina Barcodes: Toward Smart Optical Biosensors

Nanoporous Anodic Alumina Barcodes: Toward Smart Optical Biosensors

Optical Properties of Nanoporous Anodic Alumina and Derived Applications

GaN-based lamb-wave mass-sensors on silicon substrates

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