2011
DOI: 10.1016/j.snb.2011.03.060
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Detection of protein aggregation with a Bloch surface wave based sensor

Abstract: a b s t r a c tWe present the innovative application of a Bloch surface wave based sensor to the detection of protein aggregation. In Hen Egg White Lysozyme (HEWL) solutions, aggregates are discriminated from the monomeric forms in a label-free detection scheme.

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Cited by 68 publications
(42 citation statements)
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“…They have received much attention in recent years, mostly because of their potential in sensing. BSW-based gas, protein, antibody, glucose, and protease detectors as well as BSW-induced enhanced Raman scattering have been successfully demonstrated [6][7][8][9][10][11][12][13]. Different effects in the presence of BSWs have been experimentally observed including the enhancement of fluorescence [14] and magneto-optical effects [15], giant Goos-Hänchen effect [16], and BSW-induced radiation forces [17,18].…”
Section: Introductionmentioning
confidence: 99%
“…They have received much attention in recent years, mostly because of their potential in sensing. BSW-based gas, protein, antibody, glucose, and protease detectors as well as BSW-induced enhanced Raman scattering have been successfully demonstrated [6][7][8][9][10][11][12][13]. Different effects in the presence of BSWs have been experimentally observed including the enhancement of fluorescence [14] and magneto-optical effects [15], giant Goos-Hänchen effect [16], and BSW-induced radiation forces [17,18].…”
Section: Introductionmentioning
confidence: 99%
“…Thanks to these properties, BSWs are naturally suited for label-free, fluorescence sensing applications, and, in this context, they have widely expressed their capability in the last decades [1][2][3][4][5][6][7]. Moreover, recent papers have investigated their potentialities for on-chip guiding and manipulation of an optical signal propagating on a 1D photonic crystal [8][9][10][11][12][13][14].…”
Section: Introductionmentioning
confidence: 99%
“…Bloch surface waves (BSWs) have already shown their potential as probes in sensing experiments [1][2][3]. The great advantages of such electromagnetic surface waves come from the all-dielectric platform on which they are generated [4] and from the long propagation length they offer compared to surface plasmon polaritons [5].…”
Section: Introductionmentioning
confidence: 99%