Detection of polypeptides of Hepatitis B virus (Dane paticles) and their core paticles using SDS-polyacrylamide gel electrophoresis

賢浩, 赤羽

doi:10.2957/kanzo.19.371

Acta hepatologica Japonica

1978

DOI: 10.2957/kanzo.19.371

|View full text |Cite

Detection of polypeptides of Hepatitis B virus (Dane paticles) and their core paticles using SDS-polyacrylamide gel electrophoresis

赤羽賢浩¹

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1979

Publication Types

Select...

Article1

Relationship

Self Cite0

Independent1

Authors

Journals

Cited by 1 publication

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Incidence and clinical significance of HBe antigen and antibody in HBsAg-positive various liver diseases

et al. 1979

View full text Add to dashboard Cite

The HBeAg was detected in 5 of 24 patients with acute type B hepatitis (20.8%), 33 of 95 with chronic hepatitis (34.7%), 6 of 33 with liver cirrhosis (18.2%), and 3 of 39 with hepatocellular carcinoma (7.7%). On the other hand, anti-HBe was found in 4.2% of acute hepatitis, 18.9% of chronic hepatitis, 9.1% of liver cirrhosis, and 12.8% of hepatocellular carcinoma. We found that an early detection of HBeAg in patients with acute hepatitis is of no prognostic value, but its persistence may provide the earliest evidence of potential chronicity. In chronic liver diseases, HBeAg-positive cases showed remarkable fluctuations of serum transaminase levels, severe histological changes and poor responses to treatment. Many of the HBeAg-positive patients lost their initial positivity of HBeAg within six months or one year and in some cases serocoverted to anti-HBe after acute exacerbation. Follow-up study more than several years revealed that the presence of anti-HBe reflect an inactive stage and a more favorable outcome, whereas persistence of HBeAg may provide an active and continuing hepatocellular damage. From these results, we believed that serial measurements of HBeAg/anti-HBe system are useful prognostic marker in patients with HBsAg-positive liver disease.

show abstract

Incidence and clinical significance of HBe antigen and antibody in HBsAg-positive various liver diseases

et al. 1979

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Detection of polypeptides of Hepatitis B virus (Dane paticles) and their core paticles using SDS-polyacrylamide gel electrophoresis

Cited by 1 publication

References 19 publications

Incidence and clinical significance of HBe antigen and antibody in HBsAg-positive various liver diseases

Incidence and clinical significance of HBe antigen and antibody in HBsAg-positive various liver diseases

Contact Info

Product

Resources

About