Detection of Pathological Change in Dystrophic Muscle With B-Scan Ultrasound Imaging

Heckmatt, J. Z.; Dubowitz, Victor; Leeman, S.

doi:10.1016/s0140-6736(80)92656-2

Cited by 156 publications

(84 citation statements)

References 3 publications

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“…In 1980 it was first discovered that diseased muscles showed a different appearance on ultrasound compared to healthy muscles. 38 Subsequently, several studies have established high sensitivities and specificities of ultrasound in the detection of neuromuscular disorders. 24,39,42,55,67,74,98 Currently, ultrasound is widely available and ultrasound techniques have further improved, resulting in display of muscle tissue with resolutions up to 0.1 mm.…”

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confidence: 99%

Muscle ultrasound in neuromuscular disorders

2008

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Muscle ultrasound is a useful tool in the diagnosis of neuromuscular disorders, as these disorders result in muscle atrophy and intramuscular fibrosis and fatty infiltration, which can be visualized with ultrasound. Several prospective studies have reported high sensitivities and specificities in the detection of neuromuscular disorders. Although not investigated in large series of patients, different neuromuscular disorders tend to show specific changes on muscle ultrasound, which can be helpful in differential diagnosis. For example, Duchenne muscular dystrophy results in a severe, homogeneous increase of muscle echo intensity with normal muscle thickness, whereas spinal muscular atrophy shows an inhomogeneous increase of echo intensity with severe atrophy. A major advantage of muscle ultrasound, compared to other imaging techniques, is its ability to visualize muscle movements, such as muscle contractions and fasciculations. This study reviews the possibilities and limitations of ultrasound in muscle imaging and its value as a diagnostic tool in neuromuscular disorders.

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Muscle ultrasound in neuromuscular disorders

2008

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“…Since then, the technique of ultrasound has rapidly evolved, leading to its widespread use in almost all fields of medicine because of its non-invasive nature and real-time display. In 1980 it was first discovered that diseased muscles showed a different ultrasound appearance compared to healthy muscles [11]. Next to neuromuscular disorders, malignancies, infections and hematomas and ruptures of the musculoskeletal system can also be detected with ultrasound [7,9,10,24].…”

Section: Ultrasound Of Normal Muscle Tissue 2 Muscle Ultrasound In Nmentioning

confidence: 99%

Skeletal muscle ultrasound

Pillen

2010

Eur J Transl Myol

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Muscle ultrasound is a convenient technique to visualize normal and pathological muscle tissue as it is non-invasive and real-time. Neuromuscular disorders give rise to structural muscle changes that can be visualized with ultrasound: atrophy can be objectified by measuring muscle thickness, while infiltration of fat and fibrous tissue increase muscle echo intensity, i.e. the muscles become whiter on the ultrasound image. Muscle echo intensity need to be quantified to correct for age-related increase in echo intensity and differences between individual muscles. This can be done by gray scale analysis, a method that can be easily applied in daily clinical practice. Using this technique it is possible to detect neuromuscular disorders with predictive values of 90 percent. Only in young children and metabolic myopathies the sensitivity is lower. Ultrasound is a dynamic technique and therefore capable of visualizing normal and pathological muscle movements. Fasciculations can easily be differentiated from other muscle movements. Ultrasound appeared to be even more sensitive in detecting fasciculations compared to EMG and clinical observations, because it can visualize a large muscle area and deeper located muscles. With improving resolution and frame rate it has recently become clear that also smaller scale spontaneous muscle activity such as fibrillations can be detected by ultrasound. This opens the way to a broader use of muscle ultrasound in the diagnosis of peripheral nerve and muscle disorders.

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“…Later, Kramer, Yong et al [9] conducted the first examination of the patient with muscle disease. Using ultrasound muscles in the evaluation of neuromuscular diseases started to gain interest by 1980 (Heckmatt, Dubowitz and Leeman, 1980 [6]; Heckmatt, Leeman and Dubowitz, 1982) [7].…”

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“…Позже Kramer, Yong и др. [9] провели первое обследование пациента с мышечной патологией. Исполь-зование УЗИ мышц в оценке нервно-мышечных заболеваний начало набирать популярность к 1980 году (Heckmatt, Dubowitz и Leeman, 1980 [6]; Heckmatt, Leeman и Dubowitz, 1982) [7].…”

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Методи Візуалізації М’язової Дистрофії Дюшенна (Літературний Огляд)

Руденко¹,

Pozdnyakov²,

Suslov³

2022

INJ

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Дана стаття присвячена літературному огляду методів візуалізації скелетних м’язів при м’язовій дистрофії Дюшенна. Проведено аналіз як історично значущих наукових робіт, так і останніх досягнень в галузі нейровізуалізації. У статті розглянуто такі методи, як ультразвукова діагностика, комп’ютерна та магнітно-резонансна томографія скелетних м’язів, а також магнітно-резонансна спектроскопія. Відзначено і обґрунтовано актуальність і перспективність неінвазивних, безпечних і об’єктивних методів оцінки скелетних м’язів при м’язовій дистрофії Дюшенна.

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Detection of Pathological Change in Dystrophic Muscle With B-Scan Ultrasound Imaging

Cited by 156 publications

References 3 publications

Muscle ultrasound in neuromuscular disorders

Muscle ultrasound in neuromuscular disorders

Skeletal muscle ultrasound

Методи Візуалізації М’язової Дистрофії Дюшенна (Літературний Огляд)

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