Detection of pathogenic leptospira as a cause of abortion in cattle-observations on diagnosis

Tomckowiack, Camilo; Matamala, Sebastián; León, Constanza; Moroni, Manuel; Salgado, Miguel

doi:10.4067/s0719-81322022000200077

Cited by 3 publications

(3 citation statements)

References 24 publications

(30 reference statements)

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“…Other signs that are a consequence of leptospiral infection but occur less frequently than the subclinical signs are abortions, stillbirths, or the birth of weak calves. Abortions have been widely associated with bovine leptospirosis, perhaps the most visible sign, being linked to incidental strains when occur as an outbreak, or to adapted strains when occur endemically [44]. It was suggested that abortions by leptospiral infection occur in the final third of pregnancy; however, fetal death has been reported in all stages [45].…”

Section: Pathogenesis and Clinical Manifestation In Femalesmentioning

confidence: 99%

Bovine Genital Leptospirosis: An Update of This Important Reproductive Disease

Aymée,

Mendes,

Lilenbaum

2024

Animals

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Bovine leptospirosis is an important disease that affects the reproductive sphere. Due to its high relevance for the bovine production chain in a worldwide scenario, a better understanding of the disease is crucial to reduce its negative impacts. The main agents are strains from the Sejroe serogroup, such as Hardjo and Guaricura, which lead to renal and genital infection. The genital colonization causes a chronic, silent, and subclinical reproductive syndrome, called Bovine Genital Leptospirosis (BGL). Embryonic death, estrus repetition, subfertility, and abortions are the main signs of BGL condition in females. However, although leptospires have been identified in semen, the manifestation of BGL in bulls remains to be clarified. The recommended diagnosis of BGL includes a serologic screening of the herds using the microscopic agglutination test followed by PCR of genital samples (cervicovaginal mucus, uterine fragment, or semen), especially from animals with reproductive failures. After the identification of carriers, control is carried out considering three steps: antimicrobial treatment of the carriers, environmental and reproductive management, and herd vaccination. Systematic testing, quarantine of newly arrived animals, and usage of antimicrobials in semen diluents or embryo culture media are other sanitary approaches that are encouraged to improve the control of the syndrome. Herein we discuss protocols for an efficient diagnosis and preventive procedures of BGL, which are fundamental to reducing the negative impact of the disease on cattle reproduction and its consequent economic hazards.

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Section: Pathogenesis and Clinical Manifestation In Femalesmentioning

confidence: 99%

Bovine Genital Leptospirosis: An Update of This Important Reproductive Disease

Aymée,

Mendes,

Lilenbaum

2024

Animals

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“…Difficult and frequent misdiagnosis of Leptospira infection due to similar symptoms of various others diseases makes it the most neglected infectious disease (Chancharoenthana et al 2022;Tomckowiack et al 2022). Identification of etiology and confirmation of clinical cases is particularly significant to establish proper preventive measures and appropriate treatment in the herd (Tomckowiack et al 2022;Martins and Lilenbaum 2017). For the proper diagnosis of LPS laboratory diagnosis is essential (Chancharoenthana et al 2022).…”

Section: Diagnosesmentioning

confidence: 99%

“…The global epidemiological status of LPS is fragmentary but in humans an estimated 1.03 million infection cases were reported in 2020 (Calvopiña et al 2022). It's considered as a major cause of economic loss that can be attributed to the cost of treatment, high culling and low pregnancy in animals (Tomckowiack et al 2022). The diagnoses are only a key step for a better outcome that depends on the sample availability.…”

Section: Introductionmentioning

confidence: 99%