Detection of Non-Tuberculous Mycobacteria in Mari El Republic

Петрова, Л. В.; Мельникова, Е. И.; Soloviev, Yu. A.; Ларионова, Е. Е.; SEVАSTYANOVА, E. V.

doi:10.21292/2075-1230-2018-96-2-41-46

Cited by 4 publications

(1 citation statement)

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“…Актуальными являются фундаментальные исследования нетуберкулезных микобактерий [14][15][16][17]. В ЦНИИТ исследования нетуберкулезных микобактерий направлены на создание тест-систем для ускоренной диагностики микобактериоза и изучение генома возбудителей.…”

Section: микробиология и молекулярная генетика микобактериальных инфеunclassified

Tuberculosis in the Russian Federation: Situation, Challenges and Perspectives

Ergeshov¹

2018

Annals RAMS

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Tuberculosis (TB) is a significant problem of public health both in Russia and abroad. About one third of the world’s population is infected with Mycobacterium tuberculosis. Every year more than 10 million new TB cases are registered in the world, and about 1.7 million people die from TB. In the Russian Federation, due to the measures taken by the Government and health authorities the epidemic TB situation has been noticeably improved since the sharp deterioration in the 90s of the last century. At the same time, the spread of drug-resistant TB and its low treatment effectiveness, the spread of combined HIV and TB infection reduces the effectiveness of anti-tuberculosis interventions. The research conducted by CTRI, the WHO Collaborating Center for TB in the Russian Federation, is aimed at solving such urgent problems as studying latent infection mechanisms, developing new test systems for accelerated diagnostics of drug resistance, clinical approbation and introduction of short effective regimens of chemotherapy, developing new antituberculosis agents. The achieved successes in the study of tuberculosis in the 21st century creates preconditions for eliminating its epidemic both in Russia and the world, though suggesting imminent breakthrough for tuberculosis is a hasty conclusion.

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Section: микробиология и молекулярная генетика микобактериальных инфеunclassified

Tuberculosis in the Russian Federation: Situation, Challenges and Perspectives

Ergeshov¹

2018

Annals RAMS

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Diagnosis and treatment of patients with pulmonary nontuberculous mycobacterial diseases in Arkhangelsk, Russia

Eliseev

Hinderaker

Heldal³

et al. 2019

Infection, Genetics and Evolution

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Features of radiological manifestations in the diagnosis of nontuberculous mycobacteriosis. Literature review Сlinical observation

Khomutova,

Porokh,

Novikov

et al. 2023

Medicinskaâ vizualizaciâ

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Purpose of the study. The purpose of this literature review is to determine the radiographic features in the diagnosis of non-tuberculous mycobacteriosis (NTMB) and to assess the possibility of radiological diagnosis of a combination of tuberculosis and non-tuberculous mycobacteriosis of the lungs in a patient with HIV infection.Materials and methods. A review of the literature on the bases of scientific articles PubMed, ELibrary and Google Scholar. Attention was focused on full-text articles. The article presents a clinical observation of a patient being treated at the Clinical TB Dispensary in Omsk from 2019 to 2022 with a diagnosis of disseminated pulmonary tuberculosis, bilateral, in the infiltration phase, tuberculous spondylitis ThVII–IX, complicated by a paravertebral abscess.Results. The radiological changes characteristic of NTMB are: lesion of the right middle and lingual lobes of the lungs with the presence of diffuse bronchiectasis, changes in the type of “tree in the kidneys”, compaction of lung tissue by the type of “frosted glass” with the presence of centrilobular nodules, asymmetric small dense foci with peribronchial location, apical location of thin-walled cavities with thickening of the costal pleura, as well as foci of inflammatory infiltration. The absence of specific symptoms for this pathology requires further research in this area. The identification of characteristic radiological features will speed up the diagnosis of infection and determine the correct management tactics for patients.Conclusion. The radiosemiotics of NTMB is characterized by a large variability of manifestations. The most informative method of radiation diagnosis of NTMB is multispiral computed tomography (MSCT). Thanks to MSCT, a radiologist has the opportunity to accurately assess the localization and nature of foci, as well as assess the dynamics and prevalence of the process. The most characteristic radiological symptoms are the defeat of the right middle and lingual lobes of the lungs with the presence of diffuse bronchiectasis, changes in the type of “tree in the kidneys”, compaction of lung tissue by the type of “frosted glass” and the presence of centrilobular nodules, asymmetric small dense foci with peribronchial arrangement, apical arrangement of thin-walled cavities with thickening of the costal pleura, as well as foci inflammatory infiltration. The absence of specific symptoms for this pathology requires further research in this area. The identification of characteristic radiological features will speed up the diagnosis of infection and determine the correct management tactics for patients.

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Detection of Non-Tuberculous Mycobacteria in Mari El Republic

Cited by 4 publications

References 0 publications

Tuberculosis in the Russian Federation: Situation, Challenges and Perspectives

Tuberculosis in the Russian Federation: Situation, Challenges and Perspectives

Diagnosis and treatment of patients with pulmonary nontuberculous mycobacterial diseases in Arkhangelsk, Russia

Features of radiological manifestations in the diagnosis of nontuberculous mycobacteriosis. Literature review Сlinical observation

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