Detection of mycobacterial tuberculosis DNA in lichen scrofulosorum

Lichen Scrofulosorum Mimicking Lichen Planus

“…However, in 2 patients with lichen scrofulosorum, mycobacterial DNA was detected in the cutaneous lesions by PCR procedures. 11,20 The most striking features of our patient were his epidemiological and clinical characteristics. Our patient, aged 67, is the oldest one reported in literature, and his lesions ranged between 5 and 10 mm in size, larger than the tiny follicular papules usually seen in most patients with lichen scrofulosorum.…”

“…18 Although rare, cases of lichen scrofulosorum despite having a purified protein tuberculin skin test negative have also been documented. 17,19,20 Clinically, lichen scrofulosorum is characterized by the onset of an asymptomatic eruption of multiple, tiny, pinhead-sized (1-2 mm in diameter), follicular and perifollicular papules. The papules are usually skin colored, but may be yellowish to reddish brown, and they appear flat topped, sometimes with fine scaling.…”

Lichen scrofulosorum and endometrial tuberculosis: a novel association

“…Tuberculids represent cutaneous immunologic reaction to the presence of M. tuberculosis , M. bovis , or their products in a patient with significant immunity. Although the smear and culture from the lesional skin of tuberculids are negative for M. tuberculosis , PCR techniques have identified mycobacterial DNA in the lesional tissue of all types of tuberculids, including recently from LS . LS, an infrequently reported tuberculid, was first described by Hebra in 1868 .…”

Tuberculose cutanée

“…La guérison se fait sans cicatrices [23]. Elle survient brutalement et touche préférentiellement le tronc, les membres et éventuellement la lèvre supérieure.…”

“…Elle survient brutalement et touche préférentiellement le tronc, les membres et éventuellement la lèvre supérieure. La PCR présente un intérêt majeur dans ces formes abactériennes ; elles sont positives dans plus de 50 % des cas [23]. La guérison se fait sans cicatrices [23].…”