Detection of methoxylated and hydroxylated polychlorinated biphenyls in sewage sludge in China with evidence for their microbial transformation

Sun, Jianteng; Zhu, Lizhong; Pan, Lili; Wei, Zi; Song, Yao; Zhang, Yuduo; Qu, Liping; Zhan, Yu

doi:10.1038/srep29782

Cited by 23 publications

(15 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Polychlorinated biphenyls (PCBs) belong to persistent organic pollutants (POP) 1 for their toxicity and stability against degradation in soil and water 2 , 3 . In the past decades, various technologies have been developed carried out about degradation of PCBs and its bioaccumulation 4 , 5 . Within all the methods used to degrade the PCBs, laccase was considered as an efficient route to solve the problem because the phenolic compounds were the major substrates of laccase 6 , 7 , and amount of results showed that the laccase can efficiently remove the PCBs pollutants from the water 8 , 9 .…”

Section: Introductionmentioning

confidence: 99%

Immobilizing Laccase on Different Species Wood Biochar to Remove the Chlorinated Biphenyl in Wastewater

Xia

Niu

et al. 2018

Sci Rep

View full text Add to dashboard Cite

Biochars produced from two different wood species over a microwave assisted pyrolysis process were used as novel and green-based supports for immobilizing enzyme, laccase in particular. The results obtained from FT-IR, SEM and BET measurements indicated that Maple biochar with honeycomb structure has higher surface area and pore volume than Spruce biochar; and there exist O-H, C-H, C=O and C=C groups in biochars for potential chemical modification. The best laccase immobilization conditions identified from an orthogonal experiment were pH = 3, laccase concentration 16 g/L and contact time 8 h. Under such conditions, the high immobilization yield (64.2%) and amount (11.14 mg/g) of laccase on Maple biochar were achieved, leading to the significantly improved thermal stability of laccase. Moreover, the immobilized laccase is reusable and enhanced the enzymatic degradation of 4-hydroxy-3,5-dichlorobiphenyl (71.4% yield), thus creating a promising and novel type of adsorbent in the removal of polychlorinated biphenyls from wastewater.

show abstract

Section: Introductionmentioning

confidence: 99%

Immobilizing Laccase on Different Species Wood Biochar to Remove the Chlorinated Biphenyl in Wastewater

Xia

Niu

et al. 2018

Sci Rep

View full text Add to dashboard Cite

show abstract

“…9 Sun et al (2016) detected OH-PCBs in sewage sludge in China. 12 We also reported OH-PCBs in sediments from the Indiana Harbor and Ship Canal in Indiana, USA (IHSC), in . 10 To our knowledge, there are no studies of the full suite of OH-PCBs in sediments but only small sets of those with standards available.…”

Section: ■ Introductionmentioning

confidence: 90%

Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments

Saktrakulkla

Martínez

et al. 2022

Environ. Sci. Technol.

View full text Add to dashboard Cite

We measured the concentrations of 837 hydroxylated polychlorinated biphenyls (OH-PCBs, in 275 chromatographic peaks) and 209 polychlorinated biphenyls (PCBs, in 174 chromatographic peaks) in sediments from New Bedford Harbor in Massachusetts, Altavista wastewater lagoon in Virginia, and the Indiana Harbor and Ship Canal in Indiana, USA and in the original commercial PCB mixtures Aroclors 1016, 1242, 1248, and 1254. We used the correlation between homologues and the peak responses to quantify the full suite of OH-PCBs including those without authentic standards available. We found that OH-PCB levels are approximately 0.4% of the PCB levels in sediments and less than 0.0025% in Aroclors. The OH-PCB congener distributions of sediments are different from those of Aroclors and are different according to sites. We also identified a previously unknown compound, 4-OH-PCB52, which together with 4′-OH-PCB18 made up almost 30% of the OH-PCBs in New Bedford Harbor sediments but less than 1.2% in the Aroclors and 3.3% in any other sediments. This indicates site-specific environmental transformations of PCBs to OH-PCBs. We conclude that the majority of OH-PCBs in these sediments are generated in the environment. Our findings suggest that these toxic breakdown products of PCBs are prevalent in PCB-contaminated sediments and present an emerging concern for humans and ecosystems.

show abstract

“…For instance, Rice ( Oryza sativa L. ) was reported to metabolize PCB61 into para -substituted hydroxylated PCB61 as its major metabolite, along with a minor product of para -substituted methoxy PCB61 . In addition, the microbial transformation of PCBs into hydxylated and methoxy PCBs was also proposed. , Pham et al reported a hydroxylation of PCBs with an initial attack by the biphenyl dioxygenase from wild-type strains P. pnomenusa B356 . The hydroxylated metabolites produced from para -substituted biphenyl analogs 4′-PCB-4-ol, through a 2,3-dioxygenation of the hydroxylated ring, ultimately lead to 4′-PCB-3,4,5-ol.…”

Section: Metabolic Pathway Yielding Hydroxylated and Quinone-type Met...mentioning

confidence: 99%

“…77 In addition, the microbial transformation of PCBs into hydxylated and methoxy PCBs was also proposed. 78,79 Pham et al reported a hydroxylation of PCBs with an initial attack by the biphenyl dioxygenase from wild-type strains P. pnomenusa B356. 80 The hydroxylated metabolites produced from parasubstituted biphenyl analogs 4′-PCB-4-ol, through a 2,3dioxygenation of the hydroxylated ring, ultimately lead to 4′-PCB-3,4,5-ol.…”

Section: Metabolic Pathway Yieldingmentioning

confidence: 99%

A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress

Liu

Song

et al. 2020

Chem. Res. Toxicol.

View full text Add to dashboard Cite

Polychlorinated biphenyls (PCBs) are notorious persistent organic pollutants that were banned in the last century. However, PCBs still remain ubiquitous in the ecosystem due to their persistence and bioaccumulative potency against environmental and biological degradation. Albeit there is no longer the permission of commercial production of PCBs, they were continuously released into global biota via illegal disposal of e-waste or as byproducts of industrial supplies. The role of oxidative stress is often implicated in PCBs' toxicology. PCBs, especially coplanar ones, have a high affinity toward aryl hydrocarbon receptors and inducing CYP1A1, which is considered as a source of oxidative stress. Although commercial PCBs and coplanar individual PCBs, for example, PCB 77 and 126, induced oxidative stresses have been extensively investigated, PCB metabolite-induced oxidative stress has received less attention. PCBs can undergo phase I metabolism which metabolizes the parent PCBs into hydroquinone/semiquinone/quinone metabolites as a futile redox cycle, producing downstream reactive oxygen species (ROS) as byproducts. PCBs can also undergo phase II metabolism yielding methylsulfonyl metabolites that deplete glutathione and such. PCB metabolites induce oxidative stress generally via direct production of ROS or indirect scavenge antioxidant and inhibit antioxidant enzymes, disturbing cellular redox balance. This review aims to provide a critical summary of PCBs metabolism, PCBs parents, and daughter metabolite-induced oxidative stress. We especially focus on the connection between parent PCBs and downstream metabolites, to encourage research associated with PCB metabolite-induced oxidative stress.

show abstract

Detection of methoxylated and hydroxylated polychlorinated biphenyls in sewage sludge in China with evidence for their microbial transformation

Cited by 23 publications

References 47 publications

Immobilizing Laccase on Different Species Wood Biochar to Remove the Chlorinated Biphenyl in Wastewater

Immobilizing Laccase on Different Species Wood Biochar to Remove the Chlorinated Biphenyl in Wastewater

Hydroxylated Polychlorinated Biphenyls Are Emerging Legacy Pollutants in Contaminated Sediments

A Critical Review of Polychlorinated Biphenyls Metabolism, Metabolites, and Their Correlation with Oxidative Stress

Contact Info

Product

Resources

About