Detection of Metastatic Fibro-Lamellar Type of Hepato Cellular Carcinoma in Ascitic Fluid Cytology in a Liquid-Based Preparation

Abstract

Hepato cellular carcinoma (HCC) of fibro lamellar type is an uncommon primary hepatic carcinoma. They occur most commonly in young adults. Their etiology is not clear till date, as they are not associated with chronic liver disease. Fibro lamellar HCC is not an indolent tumor, but has a better prognosis than conventional HCC. We present an interesting case of metastatic fibro lamellar HCC detected in ascitic fluid prepared by liquid-based cytology (LBC). The diagnosis was confirmed by ultrasound-guided fine needle aspiration (US-FNA) of retroperitoneal lymph node. We report a rare case of fibro lamellar HCC detected on exfoliative cytology, which was confirmed by FNAC and immunochemistry (IHC). Keywords