Detection of &lt;i&gt;Mycobacterium avium&lt;/i&gt; subsp. &lt;i&gt;paratuberculosis&lt;/i&gt; in kidney samples of red deer (&lt;i&gt;Cervus elaphus&lt;/i&gt;) in Portugal: Evaluation of different methods

Matos, A.C.; Figueira, L.; Martins, Maria Helena; Matos, Manuela; Álvares, S.; Mendes, Adélio; Pinto, Maria de Lurdes; Coelho, Ana Cláudia

doi:10.1292/jvms.16-0153

Cited by 7 publications

(2 citation statements)

References 30 publications

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“…Gross evaluation of the integument was performed initially, and any lesions were noted. Then post-mortem proceeded systematically from head to tail [20,21]. The trachea, lung lobes, bronchial lymph nodes and mediastinal lymph nodes were assessed.…”

Section: Post-mortem Examinationmentioning

confidence: 99%

Mongoose (Herpestes auropunctatus) May Not Be Reservoir Hosts for Mycobacterium bovis in Fiji Despite High Population Density and Direct Contact with Cattle

Hayton

Whittington

Wakelin

et al. 2019

Veterinary Sciences

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The presence of a wildlife reservoir for Mycobacterium bovis complicates the eradication of bovine tuberculosis (BTB) from domestic cattle populations. For the BTB eradication program in Fiji, there is concern about the small Indian mongoose (Herpestes auropunctatus), which is overabundant and in direct contact with cattle. Consequently, a survey of mongooses trapped on three BTB affected dairy farms led to necropsy of 85 mongooses during January–February 2017. Thirty (35%) mongooses had gross pathological changes including possible granulomas detected at necropsy, and tissues from these animals were taken for histopathological examination. Granulomatous lesions were present in 53% of animals examined histopathologically but acid-fast bacilli were not observed and the majority of lesions in lung and kidney were associated with the nematodes Pulmostrongylus herpestis and Capillaria sp., respectively. Nevertheless, assuming test sensitivity of 35% for the current study, from this sample of 85 mongooses it can be concluded with 95% confidence that if present in the mongoose population susceptible to trapping, M. bovis prevalence was ≤10%. The prevalence of intercurrent lesions raised concerns about gross pathology as a screening test for M. bovis infection in mongooses in Fiji, and therefore pathogen detection methods such as bacterial culture and direct tissue PCR are recommended for future surveys. These are needed to completely rule out the mongoose as a reservoir host for M. bovis in Fiji.

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Section: Post-mortem Examinationmentioning

confidence: 99%

Mongoose (Herpestes auropunctatus) May Not Be Reservoir Hosts for Mycobacterium bovis in Fiji Despite High Population Density and Direct Contact with Cattle

Hayton

Whittington

Wakelin

et al. 2019

Veterinary Sciences

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“…13,27,37 Elsewhere, both captive and free-ranging MAP-infected deer populations have been found. 29,34,44,48,49 Both bovine and ovine strains of MAP exist, differing in host preference and necessary culture conditions for isolation, with the ovine strain being more difficult to isolate. 7,46 Cattle are relatively resistant to infection with ovine strains; ovine strains readily infect sheep.…”

Section: Introductionmentioning

confidence: 99%

Characteristics of subclinicalMycobacterium aviumssp.paratuberculosisinfection in a captive white-tailed deer herd

et al. 2019

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Paratuberculosis (Johne’s disease) is caused by Mycobacterium avium ssp. paratuberculosis (MAP), and affects both domestic and wild ruminants, including cattle, goats, sheep, and deer. In cattle, most infections occur during calfhood followed by a prolonged incubation period of 1–2 y or more before cows shed culturable numbers of MAP bacilli in their feces. As disease progresses, infected animals develop protein-losing enteropathy, intractable diarrhea, and weight loss. In a cohort of 32 clinically normal deer from a herd with a history of periodic clinical paratuberculosis, we found that subclinical infection was characterized by high rates of infection, common involvement of mesenteric lymph nodes, minimal lesion formation, few intralesional acid-fast bacilli, and low-level fecal shedding of MAP. The characteristics of subclinical paratuberculosis in white-tailed deer resemble those of cattle and red deer, although microscopic lesions were less common in subclinical deer than reported for subclinical cattle, and we did not see necrotizing granulomas as described in subclinical red deer and elk.

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Diseases of the urinary system

Jones¹,

Miesner²,

Edmondson³

2021

Sheep, Goat, and Cervid Medicine

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Detection of <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i> in kidney samples of red deer (<i>Cervus elaphus</i>) in Portugal: Evaluation of different methods

Cited by 7 publications

References 30 publications

Mongoose (Herpestes auropunctatus) May Not Be Reservoir Hosts for Mycobacterium bovis in Fiji Despite High Population Density and Direct Contact with Cattle

Mongoose (Herpestes auropunctatus) May Not Be Reservoir Hosts for Mycobacterium bovis in Fiji Despite High Population Density and Direct Contact with Cattle

Characteristics of subclinicalMycobacterium aviumssp.paratuberculosisinfection in a captive white-tailed deer herd

Diseases of the urinary system

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