Detection of IgG on glioblastoma cell surfacein vivo

Kirsch, Wolff M.

doi:10.1007/bf01809228

Cited by 11 publications

(1 citation statement)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Populations of B lymphocytes are present within gliomas, but their ability to produce anti-glioma antibodies capable of participating in complement dependent or antibody dependent cell-mediated cytotoxic responses is doubtful [1,23]. Several laboratories have demonstrated the presence of limited antiglioma activity within the sera of a small number of patients harboring CNS gliomas [7,21,26,36]. They have reported that this activity is stronger in patients with low grade gliomas and that it may be constituted by an IgG or IgM antibody.…”

Section: Humoral Immune Responsementioning

confidence: 99%

Immunobiology of brain tumors

Frank¹,

Tribolet

1986

Neurosurg. Rev.

View full text Add to dashboard Cite

The treatment of the cerebral glioma continues to challenge neurosurgeons and basic scientists. The lack of major success with chemotherapy and radiation therapy has spurred further investigation into the biology of this tumor and host reactions to it. Much of this research has centred upon evaluation of tumor cell antigenicity and the cellular immune responses to the glioma. Contrary to previous considerations evidence suggests that astrocytes, glioma cells and tumor endothelial cells may all have pivotal roles in the initiation and prolongation of both local and systemic immune responses to the tumor. In this review we will discuss the immunobiology of the glioma with specific reference to the interactions between the tumor and the host immune system. In addition, ideas for potential therapeutic manipulation of the host-glioma immune interactions will be reviewed stressing potential pitfalls and risks.

show abstract

Section: Humoral Immune Responsementioning

confidence: 99%

Immunobiology of brain tumors

Frank¹,

Tribolet

1986

Neurosurg. Rev.

View full text Add to dashboard Cite

show abstract

Immunologic Considerations of Patients with Brain Tumors

MahaleyJr.¹,

Gillespie²

1983

Cancer Treatment and Research

View full text Add to dashboard Cite

Immunology of gliomas

Tribolet¹

1989

Child's Nerv Syst

View full text Add to dashboard Cite

The treatment of cerebral gliomas continues to challenge neurosurgeons and research scientists. The lack of major success with chemotherapy and radiation therapy has given rise to further investigation into the biology of these tumors and host reactions to them. Much of this research has centered upon the evaluation of tumor cell antigenicity and on both the humoral and cellular immune responses to gliomas. Contrary to previous considerations, evidence suggests that astrocytes, glioma cells, and tumor endothelial cells may all have pivotal roles in the initiation and prolongation of both local and systemic immune responses to the tumor. In this review we will discuss the immunobiology of the glioma with specific reference to the interactions between the tumor and the host immune system. In addition, ideas for potential therapeutic manipulation of the host-glioma immune interactions will be reviewed, stressing potential pitfalls and risks.

show abstract

Detection of IgG on glioblastoma cell surfacein vivo

Cited by 11 publications

References 14 publications

Immunobiology of brain tumors

Immunobiology of brain tumors

Immunologic Considerations of Patients with Brain Tumors

Immunology of gliomas

Contact Info

Product

Resources

About