Detection of<i>Toxocara</i>by computed tomography

Dupas, B.; Barrier, J.; Barre, Peter S.

doi:10.1259/0007-1285-59-701-518

Cited by 21 publications

(15 citation statements)

References 11 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Imaging techniques such as computed tomography and magnetic resonance imaging (MRI) are very useful tools for detecting and localizing lesions caused by migrating Toxocara sp. larvae in neural tissues, thus supporting a tentative diagnosis of NT (134)(135)(136)(137). In fact, the more sensitive MRI method can reveal granulomas as hyperintensities on T2-weighted MRI sequences, located mainly cortically or subcortically in brain areas (134,137,138).…”

Section: Global Cases Of Human Cerebral Toxocariasis With Various Neumentioning

confidence: 84%

“…larvae in neural tissues (134)(135)(136)(137)(138). MRI images of the brain may show clearly defined, multifocal lesions with strong contrast enhancement or, for persistent infections, both diffuse and circumscribed changes, but these are nonspecific findings.…”

Section: Eosinophilic Meningoencephalitis Meningitis and Encephalitismentioning

confidence: 99%

“…After treatment with mebendazole, the neurological abnormalities were resolved completely. In several meningomyelitis cases, MRI of the spine showed solitary or multiple hyperintense lesions on T2-weighted images, with strong homogeneous enhancement (125,136,146). In a particularly unusual set of clinical cases, evidence for T. canis brain invasion was reported for patients who suffered from chronic Viliuisk encephalomyelitis (VE).…”

Section: Myelitismentioning

confidence: 99%

See 2 more Smart Citations

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

et al. 2015

View full text Add to dashboard Cite

SUMMARY Toxocara canis and T. cati are highly prevalent nematode infections of the intestines of dogs and cats. In paratenic hosts, larvae do not mature in the intestine but instead migrate through the somatic tissues and organs of the body. The presence of these migrating larvae can contribute to pathology. Toxocara larvae can invade the brains of humans, and while case descriptions of cerebral toxocariasis are historically rare, improved diagnosis and greater awareness have contributed to increased detection. Despite this, cerebral or neurological toxocariasis (NT) remains a poorly understood phenomenon. Furthermore, our understanding of cognitive deficits due to toxocariasis in human populations remains particularly deficient. Recent data describe an enhanced expression of biomarkers associated with brain injury, such as GFAP, AβPP, transforming growth factor β1 (TGF-β1), NF-L, S100B, tTG, and p-tau, in mice receiving even low doses of Toxocara ova. Finally, this review outlines a hypothesis to explore the relationship between the presence of T. canis larvae in the brain and the progression of Alzheimer's disease (AD) due to enhanced AD-associated neurodegenerative biomarker expression.

show abstract

Section: Global Cases Of Human Cerebral Toxocariasis With Various Neumentioning

confidence: 84%

Section: Eosinophilic Meningoencephalitis Meningitis and Encephalitismentioning

confidence: 99%

Section: Myelitismentioning

confidence: 99%

See 1 more Smart Citation

Cerebral Toxocariasis: Silent Progression to Neurodegenerative Disorders?

et al. 2015

View full text Add to dashboard Cite

show abstract

“…Rarely, the larvae reach the systemic circulation and can lodge in any part of the body. A diagnosis of hepatic granulomata secondary to VLM has rarely been confirmed radiologically in the living host [7][8][9]. Diagnosis is usually made on the basis of clinical presentation, eosinophilia, immunological tests, and/or biopsy [3,7,8,10].…”

Section: Discussionmentioning

confidence: 99%

Hepatic granulomas due to visceral larva migrans in adults: Appearance on US and MRI

et al. 1994

View full text Add to dashboard Cite

Visceral larva migrans is a syndrome characteristically involving children with a history of pica, and usually presents with fever, abdominal pain, tender hepatomegaly, and hypereosinophilia. Hepatic granulomas of visceral larva migrans are rare in adults. We describe three adult patients with hepatic lesions which on histopathology demonstrated characteristic granulomas of visceral larva migrans. All patients had abdominal sonograms and two had additional MR scans of the liver. Both ultrasound and magnetic resonance imaging demonstrated characteristic appearances which have not been described previously (viz., ill-defined central necrotic areas surrounded by concentric thick walls and perifocal edema in the liver parenchyma).

show abstract

“…Using computed tomography (CT), hepatic lesions appear as low-density areas, as shown in Fig. 1 (Dupas et al, 1986;Ishibashi et al, 1992). In the CNS, more sensitive magnetic resonance imaging (MRI) has revealed granulomas appearing as hyper-intense areas on T 2 -weighted images, primarily located cortically or sub-cortically (Ruttinger and Hadidi, 1991).…”

Section: Diagnosis Radiologymentioning

confidence: 99%