Detection of hypertrophic cardiomyopathy is improved when using advanced rather than strictly conventional 12-lead electrocardiogram

Potter, Samara L; Holmqvist, Fredrik; Platonov, Pyotr G.; Steding, Katarina; Arheden, Håkan; Pahlm, Olle; Starc, Vito; McKenna, William J.; Schlegel, Todd T.

doi:10.1016/j.jelectrocard.2010.08.010

Cited by 36 publications

(21 citation statements)

References 42 publications

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“…For example, screening athletes for sudden cardiac death is enhanced when using athlete-specific ECG criteria rather than routine criteria, leading to fewer false positive tests, and potentially lower anxiety or need for more sophisticated imaging tests (i.e. higher sensitivity leading to improved patient outcomes and lower costs potentially) [19]. Yet, even small false positive rates can have profound adverse effects.…”

Section: Resultsmentioning

confidence: 99%

More Than Just Accuracy: A Novel Method to Incorporate Multiple Test Attributes in Evaluating Diagnostic Tests Including Point of Care Tests

Thompson

Weigl

Fitzpatrick

et al. 2016

IEEE J. Transl. Eng. Health Med.

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Current frameworks for evaluating diagnostic tests are constrained by a focus on diagnostic accuracy, and assume that all aspects of the testing process and test attributes are discrete and equally important. Determining the balance between the benefits and harms associated with new or existing tests has been overlooked. Yet, this is critically important information for stakeholders involved in developing, testing, and implementing tests. This is particularly important for point of care tests (POCTs) where tradeoffs exist between numerous aspects of the testing process and test attributes. We developed a new model that multiple stakeholders (e.g., clinicians, patients, researchers, test developers, industry, regulators, and health care funders) can use to visualize the multiple attributes of tests, the interactions that occur between these attributes, and their impacts on health outcomes. We use multiple examples to illustrate interactions between test attributes (test availability, test experience, and test results) and outcomes, including several POCTs. The model could be used to prioritize research and development efforts, and inform regulatory submissions for new diagnostics. It could potentially provide a way to incorporate the relative weights that various subgroups or clinical settings might place on different test attributes. Our model provides a novel way that multiple stakeholders can use to visualize test attributes, their interactions, and impacts on individual and population outcomes. We anticipate that this will facilitate more informed decision making around diagnostic tests.

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Section: Resultsmentioning

confidence: 99%

More Than Just Accuracy: A Novel Method to Incorporate Multiple Test Attributes in Evaluating Diagnostic Tests Including Point of Care Tests

Thompson

Weigl

Fitzpatrick

et al. 2016

IEEE J. Transl. Eng. Health Med.

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show abstract

“…Such a multi-parametric approach might initially be based on parameters of ECG alone, for example the use of the spatial QRS-T angle result in optimal combination with results from other ECG parameters [26], or it could include the use of such ECGs as screening gatekeepers for more expensive yet diagnostically definitive echocardiography tests.…”

Section: Discussionmentioning

confidence: 99%

Differentiating hypertrophic cardiomyopathy from athlete's heart: An electrocardiographic and echocardiographic approach

Grazioli

Usín

Trucco

et al. 2016

Journal of Electrocardiology

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“…T-/R-peak cloud volume Patients with structural heart disease and ICD (n = 81) Higher volume of T-peak cloud appeared to be associated with higher risk of sustained ventricular tachyarrhythmias. [69] 1. Spatial QRS-T angle 2.…”

Section: Beat-to-beat Vcg-based Parametersmentioning

confidence: 99%

A review of beat-to-beat vectorcardiographic (VCG) parameters for analyzing repolarization variability in ECG signals

Hasan¹,

Abbott²

2016

Biomedical Engineering / Biomedizinische Technik

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Elevated ventricular repolarization lability is believed to be linked to the risk of ventricular tachycardia/ventricular fibrillation. However, ventricular repolarization is a complex electrical phenomenon, and abnormalities in ventricular repolarization are not completely understood. To evaluate repolarization lability, vectorcardiography (VCG) is an alternative approach where the electrocardiographic (ECG) signal can be considered as possessing both magnitude and direction. Recent research has shown that VCG is advantageous over ECG signal analysis for identification of repolarization abnormality. One of the key reasons is that the VCG approach does not rely on exact identification of the T-wave offset, which improves the reproducibility of the VCG technique. However, beat-to-beat variability in VCG is an emerging area for the investigation of repolarization abnormality though not yet fully realized. Therefore, the purpose of this review is to explore the techniques, findings, and efficacy of beat-to-beat VCG parameters for analyzing repolarization lability, which may have potential utility for further study.

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Detection of hypertrophic cardiomyopathy is improved when using advanced rather than strictly conventional 12-lead electrocardiogram

Abstract: "Detection of hypertrophic cardiomyopathy is improved when using advanced rather than strictly conventional 12-lead electrocardiogram"

Cited by 36 publications

References 42 publications

More Than Just Accuracy: A Novel Method to Incorporate Multiple Test Attributes in Evaluating Diagnostic Tests Including Point of Care Tests

More Than Just Accuracy: A Novel Method to Incorporate Multiple Test Attributes in Evaluating Diagnostic Tests Including Point of Care Tests

Differentiating hypertrophic cardiomyopathy from athlete's heart: An electrocardiographic and echocardiographic approach

A review of beat-to-beat vectorcardiographic (VCG) parameters for analyzing repolarization variability in ECG signals

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