Abstract:Objective. To determine the correlation between the detection of human immunodeficiency virus type 1 (HIV-1) in breast milk, the duration of breastfeeding, and vertical transmission of HIV-1 infection in Ugandan women.
Methods. A prospective study of HIV-1 infection in pregnant Ugandan women and their infants has been ongoing since 1990 with follow-up of mother-infant pairs for at least 2 years. Expressed breast milk specimens were collected from 201 HIV-1-seropositive and 86 HIV-1-seronegative … Show more
“…In a study of 201 seropositive Ugandan women, Guay et al (30) attempted to detect p24 antigen and DNA in a single sample of breast milk collected approximately 6 weeks postpartum. p24 antigen was not detected in any breast milk sample, even after immune complex dissociation.…”
Section: Risk Factors For Breast‐feeding Transmissionmentioning
“…In a study of 201 seropositive Ugandan women, Guay et al (30) attempted to detect p24 antigen and DNA in a single sample of breast milk collected approximately 6 weeks postpartum. p24 antigen was not detected in any breast milk sample, even after immune complex dissociation.…”
Section: Risk Factors For Breast‐feeding Transmissionmentioning
Our data suggest that the risk of HIV infection is highest in the early months of breastfeeding, which should be considered in formulating breastfeeding policy recommendations.
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