Detection of human IgG antibodies against free N-acetyl-l-cysteine

Synthetic peptide, a fragment of the β-subunit of chorionic gonadotropin, inhibits mitogen-stimulated proliferation of human lymphocytesin vitro

“…3). For HCG, the dissociation constant was 6.3x10 "9 M and the number of binding sites was 1600 per cell. For tyrosyl-CTP, the dissociation constant was 10 -s M and the number of binding sites was 3500 per cell.…”

“…It was reported that HCG not only fulfils the luteinizing function and stimulates production of steroid hormones but also possesses immunomodulating activity. However, there is controzversy over the effect of HCG on immunocompetent cells [6,10], and the mechanisms of HCG action are unclear.Since the C-terminal sequence of HCG [3-subunit is unique for this hormone [2] it seems reasonable to study the contribution of this fragment to biological activity of HCG. Previously, it was shown that this fragment is not necessary for the interaction between HCG and the gonad cell receptors, intracellular cAMP increase, and induction of steroid hormone synthesis in vitro [7].…”