Detection of hepatic masses in patients with carcinoma: comparative sensitivities of sonography, CT, and MR imaging.

Wernecke, K; Rummeny, EJ; Bongartz, Georg; Vassallo, Pierre; Kivelitz, Dietmar; Wiesmann, William P.; Peters, P. E.; Reers, B.; Reiser, M. F.; Pircher, W

doi:10.2214/ajr.157.4.1892027

Cited by 254 publications

(106 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Although ultrasound (US) has long been considered inferior to computed tomography (CT) and magnetic resonance imaging (MRI), 10,11 new US imaging techniques, especially contrast-enhanced techniques, have changed this view. [12][13][14][15] Contrast-enhanced US (CEUS) has been demonstrated to significantly improve the detection of liver metastases in comparison with B-mode US, including a multicenter trial study.…”

mentioning

confidence: 99%

Contrast-enhanced ultrasound of histologically proven liver hemangiomas

et al. 2007

View full text Add to dashboard Cite

Differentiation of small and atypical hemangiomas from other hepatic masses using imaging methods can be difficult, especially in patients with underlying malignant disease. Therefore, contrast-enhanced ultrasound was assessed in patients with histologically confirmed hemangiomas with respect to contrast-enhancing kinetics and tumor characteristics. In 58 patients with indeterminate hepatic lesions demonstrated with at least 2 imaging methods (ultrasound/computed tomography/magnetic resonance imaging), ultrasound-guided liver biopsy revealed hemangioma. In all patients a hepatic neoplasm had been suspected because of underlying malignant disease (n ‫؍‬ 41), liver cirrhosis (n ‫؍‬ 15), or growth of the lesion (n ‫؍‬ 2). All patients underwent nonlinear, low mechanical index real-time contrast-enhanced ultrasound scanning with bolus injections of SonoVue. Peripheral nodular arterial enhancement was detected in 43 patients (74%), whereas the typical metastatic peripheral rim-like enhancement was not observed at all. Strong homogenous arterial enhancement was found in 9 of 58 (16%) patients. In 6 patients (10%), the arterial contrast enhancement pattern could not be determined because of the very small size of the lesions or fibrotic nodules. Forty-five (78%) of the hemangiomas showed homogenous centripetal filling within 180 seconds. Conclusion: Contrast-enhanced ultrasound demonstrates typical hemangioma imaging characteristics, that is, peripheral nodular contrast enhancement and iris-diaphragm sign in a high percentage of patients with undetermined lesions. This technique may therefore improve noninvasive functional characterization and differentiation of hemangiomas. (HEPATOLOGY 2007;45:1139-1145

show abstract

mentioning

confidence: 99%

Contrast-enhanced ultrasound of histologically proven liver hemangiomas

et al. 2007

View full text Add to dashboard Cite

show abstract

“…[1][2][3] It is our experience that patient habitus and isoechoic lesions are the most common ultrasonographic imaging difficulties. Of note, previous studies suggested that neither ultrasonography nor computed tomography (CT) could detect all lesions in the liver when these imaging modalities were compared with intraoperative findings.…”

mentioning

confidence: 99%

“…Of note, previous studies suggested that neither ultrasonography nor computed tomography (CT) could detect all lesions in the liver when these imaging modalities were compared with intraoperative findings. 1,2 The sensitivity of ultrasonography increases when liver lesions are larger than 15 mm in diameter. 1,2 Although we know that ultrasonography has a high spatial resolution, a tumor can be missed when it has the same or similar acoustic behavior as that of the surrounding liver tissue.…”

mentioning

confidence: 99%

“…1,2 The sensitivity of ultrasonography increases when liver lesions are larger than 15 mm in diameter. 1,2 Although we know that ultrasonography has a high spatial resolution, a tumor can be missed when it has the same or similar acoustic behavior as that of the surrounding liver tissue. Computed tomography is also known to have similar problems when a tumor has the same absorption rate of X rays as the surrounding liver tissue.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Detection of liver metastases: comparison of contrast‐enhanced wide‐band harmonic imaging with conventional ultrasonography.

Bernatik

Strobel²,

Hahn³

et al. 2001

J of Ultrasound Medicine

View full text Add to dashboard Cite

Objective. To compare the detection rate of conventional ultrasonography and contrast-enhanced wide-band harmonic ultrasonographic imaging in the detection of small liver metastases. Methods. Consecutive patients with histologically proved gastrointestinal carcinoma liver metastases were studied. Biphasic helical computed tomography, conventional ultrasonography, and contrast-enhanced wide-band harmonic imaging were performed on all patients within a 5-day period. The biphasic helical computed tomographic scans were reviewed and interpreted by a skilled radiologist. The number of lesions and their descriptive characteristics were recorded for analysis. In addition, videotape recordings of the conventional ultrasonography and contrast-enhanced wide-band harmonic imaging were blindly reviewed, after which the number of detected lesions and their characteristics were then compared with those detected on biphasic helical computed tomography, considered the standard of reference. Results. Twenty-eight patients (10 female and 18 male; age range, 45-72 years) were studied. Conventional ultrasonography detected 37 (59%) of all lesions visualized by biphasic helical computed tomography. The detection rate for contrast-enhanced wide-band harmonic imaging was significantly higher (61 [97%] of 63). In our series, two 10-mm lesions near the diaphragm were not visualized by wide-band harmonic imaging. Conclusions. The use of contrast-enhanced imaging techniques significantly improves the ultrasonographic detection of liver metastases. Our results achieved the sensitivity of biphasic helical computed tomography.

show abstract

“…Although MR and spiral CT are possibly superior to dynamic incremental bolus-enhanced conventional CT (DICT) for liver lesion characterization [1][2][3][4] and for small lesion detection [5][6][7], DICT is still the most widely available and the preferred routine technique for detecting liver lesions [8,9], and several studies have reported improvement of lesion-to-liver contrast with CT Correspondence to: R. M. Marques…”

Section: Introductionmentioning

confidence: 99%