Detection of group A beta-hemolytic Streptococcus employing three different detection methods: culture, rapid antigen detecting test, and molecular assay

Santos, O. Dos; Weckx, Luc Louis Maurice; Pignatari, Antônio Carlos Campos; Pignatari, Shirley Shizue Nagata

doi:10.1590/s1413-86702003000500003

Cited by 25 publications

(38 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Santos et al (10) investigated the frequency of GAS infections by rapid test, culture, and gene probe techniques and the culture was observed the most sensitive test. Omurzakova et al (11) compared rapid antigen detection test with bacterial culture analysis and, bacterial culture analysis were observed to be more sensitive test.…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Susceptibility of Group A Β-Hemolytic Streptococci Isolated From Tonsillar Swab Samples in 5-15 Years Old Children

et al. 2014

View full text Add to dashboard Cite

Tonsillopharyngitis is a common infectious disease in the pediatric age group. Group A Beta Hemolytic Streptococcus (GAS) is a main infectious agent of pharyngitis. Optimal therapeutic approach in these patients Beş-Onbeş Yaş Grubu Çocukların Tonsil Sürüntü Orneklerinden İzole Edilen A Grubu β-Hemolitik Streptokokların 319'unda (12,3%) GAS izole edilmiştir. Penisilin, vankomisin, linezolid, sefotaksim, eritromisin, kloramfenikol ve klindamisin duyarlılık oranları sırasıyla % 100, % 100,% 100,% 100,% 97,2, %98,3 ve % 94,7

show abstract

Section: Discussionmentioning

confidence: 99%

Antibiotic Susceptibility of Group A Β-Hemolytic Streptococci Isolated From Tonsillar Swab Samples in 5-15 Years Old Children

et al. 2014

View full text Add to dashboard Cite

show abstract

“…We reviewed 30 full-text articles, of which 11 were included (Supplemental Fig 7). [46][47][48][49][50][51][52][53][54][55][56] Previous antimicrobial exposure was not mentioned in 4 studies but was assumed to be absent owing to the studies' prospective nature 51,53 and subjects' acute presentation. 55,56 Mean age was available in 6 (55%) studies and averaged 75.6 months (Supplemental Appendix 2).…”

Section: Pharyngitismentioning

confidence: 99%

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

Kronman¹,

2014

View full text Add to dashboard Cite

WHAT'S KNOWN ON THIS SUBJECT: Many pediatric acute respiratory tract infections (ARTI) are viral and do not require antimicrobial treatment. Recent estimates of antimicrobial overprescribing for these infections, defined based on the published bacterial disease prevalence among all ARTI, are not available. WHAT THIS STUDY ADDS:Based on the published bacterial prevalence rates for pediatric ARTI, antimicrobial agents are prescribed almost twice as often as expected to outpatients nationally, amounting to an estimated 11.4 million potentially preventable antimicrobial prescriptions annually. abstract BACKGROUND AND OBJECTIVES: Antimicrobials are frequently prescribed for acute respiratory tract infections (ARTI), although many are viral. We aimed to determine bacterial prevalence rates for 5 common childhood ARTI -acute otitis media (AOM), sinusitis, bronchitis, upper respiratory tract infection, and pharyngitis-and to compare these rates to nationally representative antimicrobial prescription rates for these ARTI. METHODS:We performed (1) a meta-analysis of English language pediatric studies published between 2000 and 2011 in Medline, Embase, and the Cochrane library to determine ARTI bacterial prevalence rates; and (2) a retrospective cohort analysis of children age ,18 years evaluated in ambulatory clinics sampled by the 2000-2010 National Ambulatory Medical Care Survey (NAMCS) to determine estimated US ARTI antimicrobial prescribing rates. RESULTS:From the meta-analysis, the AOM bacterial prevalence was 64.7% (95% confidence interval [CI], 50.5%-77.7%); Streptococcus pyogenes prevalence during pharyngitis was 20.2% (95% CI, 15.9%-25.2%). No URI or bronchitis studies met inclusion criteria, and 1 sinusitis study met inclusion criteria, identifying bacteria in 78% of subjects. Based on these condition-specific bacterial prevalence rates, the expected antimicrobial rescribing rate for ARTI overall was 27.4% (95% CI, 26.5%-28.3%). However, antimicrobial agents were prescribed in NAMCS during 56.9% (95% CI, 50.8%-63.1%) of ARTI encounters, representing an estimated 11.4 million potentially preventable antimicrobial prescriptions annually.

show abstract

“…For fifty years, the fundamental test is throat swap culture. It yields 90-99% positive results and it is accepted as "gold standard" in GABHS diagnosis (2,8). GABHS incidence in upper respiratory tract infections differs in between populations.…”

Section: Discussionmentioning

confidence: 99%

“…They have low mortality and high morbidity rates (1). Acute tonsillopharyngitis is one of the most common respiratory tract infection among society (2). Acute tonsillopharyngitis is approximately 75% viral and 25% bacterial in etiology.…”

Section: Introductionmentioning

confidence: 99%

The Incidence of Group a Beta Hemolytic Streptococci in Patients With Acute Exudative Tonsilitis in Istanbul, a 14-Year Period

Furuncuoglu

Başar²,

Alıcı

et al. 2016

İst Tıp Fak D

View full text Add to dashboard Cite

Empiric antibiotic therapy is still habitually prescribed to patients with acute exudative tonsillitis in many out-patient clinics in Turkey, despite many studies worldwide showed low group A beta hemolytic streptococci (GABHS) and high viral infection incidence in those patients. In this study, we tried to show the real frequency of GABHS in acute exudative tonsillitis in Istanbul over a 14-year period. Methods:In this retrospective study, we looked through the patient files with acute exudative tonsillitis who had admitted internal medicine and ear-nose-throat out-patient clinics of our hospital in Istanbul, Turkey between 2000 and 2014. We included all patients with the diagnosis of exudative tonsillitis who had a throat swap and culture. We obtained data from the results of throat swab cultures for GABHS. Demographic data and microbiological results were analyzed. Results: Results of throat swab cultures of 967 patients were enrolled in this study (525 male, 442 female; mean age 21±7 years; range 14 to 70 years). In our retrospective analysis GABHS was isolated in only 105 (10.8%) of all patients. Of those patients in whom GABHS were isolated, 56 (5.7%) were males and 49 (5.06%) females. There was no significant difference between men and women with respect to infection rate (p>0.05). Conclusion:The incidence of GABHS was also low in acute exudative tonsillitis in Istanbul over a 14-year period. Acute exudative tonsillitis was caused by GABHS in only about 10% of all our patients. Tests such as throat culture and rapid antigen test must be performed as soon as possible to confirm diagnosis when there is a suspicion of GABHS infection but routine or immediate antibiotic therapy for acute exudative tonsillitis in adults is not necessary.

show abstract

Detection of group A beta-hemolytic Streptococcus employing three different detection methods: culture, rapid antigen detecting test, and molecular assay

Cited by 25 publications

References 10 publications

Antibiotic Susceptibility of Group A Β-Hemolytic Streptococci Isolated From Tonsillar Swab Samples in 5-15 Years Old Children

Antibiotic Susceptibility of Group A Β-Hemolytic Streptococci Isolated From Tonsillar Swab Samples in 5-15 Years Old Children

Bacterial Prevalence and Antimicrobial Prescribing Trends for Acute Respiratory Tract Infections

The Incidence of Group a Beta Hemolytic Streptococci in Patients With Acute Exudative Tonsilitis in Istanbul, a 14-Year Period

Contact Info

Product

Resources

About