Detection of glucose in diabetic tears by using gold nanoparticles and MXene composite surface-enhanced Raman scattering substrates

Cui, Xiaoyu; Li, Jinming; Li, Yuting; Li, Mingyu; Qiao, Jinglong; Wang, Dong; Cao, Hui; He, Wanli; Feng, Yun; Yang, Zhou

doi:10.1016/j.saa.2021.120432

Cited by 43 publications

(20 citation statements)

References 38 publications

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“…Tear based sensing approach using nanomaterials have also gathered significant attention in the development of this kind of non-invasive biosensors [ 135 , 136 , 137 , 138 ]. Nanostructures embedded in highly sophisticated and biocompatible contact lenses are capable of detecting glucose levels accurately, sometimes having a detection limit as low as 211 nM [ 139 ].…”

Section: Nanomaterials Based Sensingmentioning

confidence: 99%

A Concise and Systematic Review on Non-Invasive Glucose Monitoring for Potential Diabetes Management

et al. 2022

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The current standard of diabetes management depends upon the invasive blood pricking techniques. In recent times, the availability of minimally invasive continuous glucose monitoring devices have made some improvements in the life of diabetic patients however it has its own limitations which include painful insertion, excessive cost, discomfort and an active risk due to the presence of a foreign body under the skin. Due to all these factors, the non-invasive glucose monitoring has remain a subject of research for the last two decades and multiple techniques of non-invasive glucose monitoring have been proposed. These proposed techniques have the potential to be evolved into a wearable device for non-invasive diabetes management. This paper reviews research advances and major challenges of such techniques or methods in recent years and broadly classifies them into four types based on their detection principles. These four methods are: optical spectroscopy, photoacoustic spectroscopy, electromagnetic sensing and nanomaterial based sensing. The paper primarily focuses on the evolution of non-invasive technology from bench-top equipment to smart wearable devices for personalized non-invasive continuous glucose monitoring in these four methods. With the rapid evolve of wearable technology, all these four methods of non-invasive blood glucose monitoring independently or in combination of two or more have the potential to become a reality in the near future for efficient, affordable, accurate and pain-free diabetes management.

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Section: Nanomaterials Based Sensingmentioning

confidence: 99%

A Concise and Systematic Review on Non-Invasive Glucose Monitoring for Potential Diabetes Management

et al. 2022

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“…The urine test is positive when the glucose concentration in the urine exceeds 500–1000 mg/L ( Duc et al, 2018 ). A plethora of methods has been developed for glucose detection, such as spectrophotometry ( Dong et al, 2021 , Hwang et al, 2018 , Journal, 2012 ), electrochemistry ( Reghunath et al, 2021 , Yoo and Lee, 2010 , Yusan et al, 2018 ), chemiluminescence ( Gao et al, 2021 , Li et al, 2017 ), fluorometry ( Han et al, 2019 , Moschou et al, 2004 , Yu et al, 2022 ), and surface-enhanced Raman spectroscopy ( Cui et al, 2022 , Sun, 2021 ). Despite these, the colorimetric method has attracted significant attention for detection due to its simplicity, lower cost, practicality, and portability ( Li et al, 2013 ).…”

Section: Introductionmentioning

confidence: 99%

Silver nanostructures prepared via novel green approach as an effective platform for biological and environmental applications

Rani

Ahmed

Singh

et al. 2022

Saudi Journal of Biological Sciences

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“…Continuous blood glucose monitoring is critical to detect and treat patients in the early stages of diabetes. Thus far, various techniques such as spectrometry 2 – 4 , fluorescence 5 – 7 , chemiluminescence 8 – 10 and electrochemistry 11 – 14 have been successfully developed to detect glucose concentration. Among the available detection methods, electrochemical method of sensing glucose poses several advantages such as low-cost, simple operation, and rapid detection progress.…”

Section: Introductionmentioning

confidence: 99%

Cu and Ni Co-sputtered heteroatomic thin film for enhanced nonenzymatic glucose detection

Barbee

Muchharla

Adedeji

et al. 2022

Sci Rep

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In this work, we report a wafer-scale and chemical-free fabrication of nickel (Ni) and copper (Cu) heteroatomic Cu–Ni thin films using RF magnetron sputtering technique for non-enzymatic glucose sensing application. The as-prepared wafer-scale Cu–Ni thin films exhibits excellent electrocatalytic activity toward glucose oxidation with a 1.86 μM detection limit in the range of 0.01 mM to 20 mM range. The Cu–Ni film shows 1.3- and 5.4-times higher glucose oxidation activity in comparison to the Cu and Ni electrodes, respectively. The improved electrocatalytic activity is attributed to the synergistic effect of the bimetallic catalyst and high density of grain boundaries. The Cu–Ni electrodes also possessed excellent anti-interference characteristics. These results indicate that Cu–Ni heteroatomic thin film can be a potential candidate for the development of non-enzymatic glucose biosensor because of its chemical free synthesis, excellent reproducibility, reusability, and long-term stability.

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Detection of glucose in diabetic tears by using gold nanoparticles and MXene composite surface-enhanced Raman scattering substrates

Cited by 43 publications

References 38 publications

A Concise and Systematic Review on Non-Invasive Glucose Monitoring for Potential Diabetes Management

A Concise and Systematic Review on Non-Invasive Glucose Monitoring for Potential Diabetes Management

Silver nanostructures prepared via novel green approach as an effective platform for biological and environmental applications

Cu and Ni Co-sputtered heteroatomic thin film for enhanced nonenzymatic glucose detection

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