Abstract:Background
Locoregional lymph node metastasis represents the first step of metastasis in colorectal carcinomas (CRC). Identifying genetic mutations that may promote metastasis will help optimize the treatment of patients at risk of lymph node metastasis.
Method
Out of 43 identified consented cases of CRCs with and without corresponding metastasis to lymph nodes; 5 cases of CRC with lymph node metastasis were retrieved and matched with another 5 cases of CRC with negative lymph node metastasis. Whole exome se… Show more
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