Detection of gastroesophageal reflux in children with cerebral palsy using combined multichannel intraluminal impedance-ph procedure

Abstract

Gastroesophageal reflux (GER) is a very common condition in children with neurological impairment and this can influence nutritional and respiratory outcomes. The aim of this study was to investigate the presence of GER in children with cerebral palsy (CP) using multiple intraluminal impedance (MII)-pH monitoring. The use of combined MII-pH allows for the detection of both acid and non-acid reflux episodes. A total of 29 CP patients with symptoms suggesting GER, aged 2 to 10 years old, underwent 24-hour combined MII-pH monitoring. There were a total of 3899 reflux episodes, of which 29% were acid, 60% were weakly acid and 11% were alkaline. The number of non-acid reflux episodes was statistically significantly greater (p<0.01). These findings confirm that GER disease is seen frequently in children with cerebral palsy and most of the reflux episodes are not acidic. Non-acid reflux can also influence the morbidity in patients with cerebral palsy. It can be concluded that 70% of the reflux episodes would not have been recognized by pH measurement alone.

Preventive Dentistry in Children with Special Needs: Narrative Review

“…Children with CP are also prone to gastroesophageal reflux disease due to poor muscle control in the lower esophageal sphincter and swallowing difficulties. This condition can cause tooth erosion 18 . Fluoride treatment helps reduce surface microhardness loss and mineral loss in enamel and dentin 19 .…”

Prevalensi Drooling, Disfagia Dan Manifestasi Oral Pada Anak Dengan Cerebral Palsy

“…6 Anak-anak CP dengan disfagia berat, anomali penelanan, penurunan laju aliran dan pH saliva, disfungsi lingual, refleks gigitan yang ber kepanjangan dan berlebihan, pengunyahan tidak memadai, bibir dan pipi tidak berfungsi, serta maloklusi. 14 Kondisi ini mengakibatkan kebersihan gigi dan kesehatan mulut terganggu. Berbagai keterbatasan ini turut mem perpanjang waktu untuk makan, mengunyah dan menelan makanan serta memeliharan keber sihan mulut.…”

Morphofunctional features of organs in children with cerebral palsy

“…По данным исследования G. Caltepe и др. у детей с ДЦП по результатам внутрипищеводной рН-импедансометрии чаще диагностировался щелочной рефлюкс [27]. Преимущество рН-импедансометрии заключается в возможности диагностики как кислого, так и слабо-кислого и щелочного рефлюксов, что позволяет выбрать правильную тактику ведения пациента [28].…”