Detection of Ebola Virus in Oral Fluid Specimens during Outbreaks of Ebola Virus Hemorrhagic Fever in the Republic of Congo

Abstract

This study demonstrates the usefulness of oral fluid samples for the investigation of Ebola outbreaks, but further development in antibodies and antigen detection in oral fluid specimens is needed before these samples are used for filovirus surveillance activities in Africa.

Isolates of Zaire ebolavirus from wild apes reveal genetic lineage and recombinants

“…The two most recent ZEBOV outbreaks occurred in RC (20). One originated in Mbandza and was associated with 35 human cases (29 deaths) between October and December 2003, and the other originated in Etoumbi, where 12 human cases (9 deaths) were reported between April and June 2005 (Fig.…”

Ebola Virüsü

“…Close contact with an acute Ebola case and receiving an injection with a reused, unsterilized syringe at the hospital were the major risk factors for virus transmission in humans5. The other reported cases are represented below in the Graph 1 [6][7][8][9][10][11][12][13][14][15][16][17][18][19] .…”

Neonatal Ebola infection: An Interesting Issue in Pediatric Infectious Disease

“…A similar, very high fatality rate among newborns was also observed (8). The possibility of perinatal infection can be seen in these cases from Congo and Uganda where there was no evidence of Ebola infection in the mother during pregnancy (7,8). Intrafamilial transmission from other members of the family to the neonates via body fluid contact is proposed (7,8).…”

“…The possibility of perinatal infection can be seen in these cases from Congo and Uganda where there was no evidence of Ebola infection in the mother during pregnancy (7,8). Intrafamilial transmission from other members of the family to the neonates via body fluid contact is proposed (7,8). In a recent publication in Am J Infect Control, the transmission of Ebola to a newborn through contact with the mother's body fluid was reported (9).…”

“…Nevertheless, Ebola infection among the newborns has been observed. According to the report from Congo by Formenty et al, the youngest case was a five-dayold newborn, and there is high mortality among newborns even when the clinical presentation is only a fever (7). In Uganda, a case was reported in a three day old.…”