Detection of distant metastases in rectal cancer: contrast-enhanced CT vs whole body MRI

Yoon, Jeong Hee; Yu, Mi Hye; Hur, Bo Yun; Park, Chang Min; Lee, Jeong Min

doi:10.1007/s00330-020-07149-1

Cited by 3 publications

(1 citation statement)

References 29 publications

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“…At present, enhanced CT scan has been used more and more widely in clinical practice. Its advantages include high image definition and fast scanning speed, which can make a more effective judgment on the location, size, and degree of invasion of the tumor and can also clearly show the metastasis of distant organs [9]. Routine magnetic resonance imaging has been widely used in preoperative staging of RC, but its accuracy and imaging characteristics have not been accurately determined [10].…”

Section: Introductionmentioning

confidence: 99%

The Clinical Value of the Combined Detection of Enhanced CT, MRI, CEA, and CA199 in the Diagnosis of Rectal Cancer

Hao

Sui

et al. 2021

Journal of Oncology

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Background. To explore the clinical value of enhanced computed tomography (enhanced CT), magnetic resonance imaging (MRI), carcinoembryonic antigen (CEA), and cancer antigen 199 (CA199) in the diagnosis of rectal cancer (RC). Methods. A total of 156 patients with RC confirmed by postoperative pathology admitted to the Affiliated Yantai Yuhuangding Hospital of Qingdao University from March 2018 to November 2020 were included in the malignant group, and 52 patients with chronic proctitis in the benign control group. All patients underwent preoperative enhanced CT, MRI scans, and serum CEA and CA199 tests. The accuracy, sensitivity, and specificity of single and combined enhanced CT, MRI, CEA, and CA199 tests for the clinical staging of RC were calculated. Results. The postoperative pathological diagnosis showed that 35 cases of 156 RC patients were at T1 stage, 29 cases were at T2 stage, 24 cases were at T3 stage, 11 cases were at T4 stage, 23 cases were at N0 stage, 21 cases were at N1 stage, 8 cases were at N2 stage, 3 cases were at M0 stage, and 2 cases were at M1 stage. The positive rate of MRI in the diagnosis of RC was higher than that of enhanced CT. Serum CEA and CA199 levels in the malignant group were significantly increased compared with the benign group. The sensitivity, specificity, and accuracy of the combined detection were significantly higher than those of the single detection. Conclusion. Compared with enhanced CT, MRI has a higher detection rate of T and N stage in patients with RC. Combined enhanced CT, MRI, CEA, and CA199 can provide more accurate diagnosis and preoperative staging of RC patients.

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Section: Introductionmentioning

confidence: 99%