Detection of CT-proved pulmonary nodules: comparison of selenium-based digital and conventional screen-film chest radiographs.

Woodard, Pamela K.; Slone, Richard M.; Sagel, S S; Fleishman, Matthew J.; Gutiérrez, Fernando R.; Reiker, Gregory G.; Pilgram, T K; Jost, Res

doi:10.1148/radiology.209.3.9844662

Cited by 23 publications

(6 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…More nodules were expected on CR than film‐screen radiographs because the use of edge‐enhancement filters in the image reconstruction algorithm, the ability to manipulate image features, and the wider dynamic range should improve contrast resolution in regions with overlapping anatomic structures . Older studies in humans have similarly shown little‐to‐no difference between digital and film‐screen radiography in the detection of pulmonary nodules . We also expected that more nodules would be found in the caudal regions on radiographs, given their larger area, greater ventilation, and fewer superimposed structures (i.e., heart, mediastinum), but this was not the situation.…”

Section: Discussionmentioning

confidence: 99%

A Comparison of Computed Tomography, Computed Radiography, and Film‐screen Radiography for the Detection of Canine Pulmonary Nodules

Alexander

Joly²,

Blond³

et al. 2012

Vet Radiology Ultrasound

View full text Add to dashboard Cite

Computed tomography (CT) has become more widely available and computed radiography (CR) has replaced film‐screen radiography for canine thoracic imaging in many veterinary practices. There are limited data comparing these modalities in a veterinary clinical setting to detect pulmonary nodules. We compared CT, CR, and film‐screen radiography for detecting the presence, number, and characteristics of pulmonary nodules in dogs. Observer performance for a variety of experience levels was also evaluated. Twenty‐one client‐owned dogs with a primary neoplastic process underwent CT and CR; nine also received film‐screen radiographs. Positive/negative classification by consensus agreed between the three modalities in 8/9 dogs and between CR and CT in the remaining 12. CT detected the greatest (P = 0.002) total number of nodules and no difference was seen between CR and films. The greatest number of nodules was seen in the right middle and both caudal regions, but only using CT (P < 0.0001). Significantly smaller nodules were detected with CT (P = 0.0007) and no difference in minimum size was detected between CR and films. Observer accuracy was high for all modalities; particularly for CT (90.5–100%) and for the senior radiologist (90.5–100%). CT was also characterized by the least interobserver variability. Although CT, CR, and film‐screen performed similarly in determining the presence or absence of pulmonary nodules, a greater number of smaller nodules was detected with CT, and CT was associated with greater diagnostic confidence and observer accuracy and agreement.

show abstract

Section: Discussionmentioning

confidence: 99%

A Comparison of Computed Tomography, Computed Radiography, and Film‐screen Radiography for the Detection of Canine Pulmonary Nodules

Alexander

Joly²,

Blond³

et al. 2012

Vet Radiology Ultrasound

View full text Add to dashboard Cite

show abstract

“…This careful recommendation is based on realistic, but experimental data. The experiment was preferred to a patient study, since a reasonable amount of raw image data from a large number of patients with histopathologic proof or at least corresponding CT is difficult to obtain [21]. Repeated exposures would have been prohibitive in patients or ethically problematic in a laboratory animal [22].…”

mentioning

confidence: 99%

Pulmonary nodule detection with digital projection radiography: an ex-vivo study on increased latitude post-processing

et al. 2006

View full text Add to dashboard Cite

To evaluate increased image latitude post-processing of digital projection radiograms for the detection of pulmonary nodules. 20 porcine lungs were inflated inside a chest phantom, prepared with 280 solid nodules of 4-8 mm in diameter and examined with direct radiography (3.0x2.5 k detector, 125 kVp, 4 mAs). Nodule position and size were documented by CT controls and dissection. Four intact lungs served as negative controls. Image post-processing included standard tone scales and increased latitude with detail contrast enhancement (log-factors 1.0, 1.5 and 2.0). 1280 sub-images (512x512 pixel) were centred on nodules or controls, behind the diaphragm and over free parenchyma, randomized and presented to six readers. Confidence in the decision was recorded with a scale of 0-100%. Sensitivity and specificity for nodules behind the diaphragm were 0.87/0.97 at standard tone scale and 0.92/0.92 with increased latitude (log factor 2.0). The fraction of "not diagnostic" readings was reduced (from 208/1920 to 52/1920). As an indicator of increased detection confidence, the median of the ratings behind the diaphragm approached 100 and 0, respectively, and the inter-quartile width decreased (controls: p<0.001, nodules: p=0.239) at higher image latitude. Above the diaphragm, accuracy and detection confidence remained unchanged. Here, the sensitivity for nodules was 0.94 with a specificity from 0.96 to 0.97 (all p>0.05). Increased latitude post-processing has minimal effects on the overall accuracy, but improves the detection confidence for sub-centimeter nodules in the posterior recesses of the lung.

show abstract

“…Ishigaki et al 10) have reported that digital and conventional radiographs were not statistically different in detecting interstitial opacities. Woodard et al showed that the sensitivity of detecting CT-proven nodules (mean diameter 1.5 cm) by digital and conventional radiographs were 66% (95%CI, 54-76%) and 64% (95%CI, 52-74), respectively 11) . A phantom study that compared the detection of test disks (diameters from 0.3 mm to 4 mm) by FPD and conventional radiograph revealed a higher detection rate by FPD than by conventional radiography 12) .…”

Section: Discussionmentioning

confidence: 99%

A Flat‐Panel Detector Digital Radiography and a Storage Phosphor Computed Radiography: Screening for Pneumoconioses

Takashima

Suganuma

Sakurazawa

et al. 2007

Journal of Occupational Health

View full text Add to dashboard Cite

A b s t r a c t : A F l a t -P a n e l D e t e c t o r D i g i t a l Radiography and a Storage Phosphor ComputedWe compared these two techniques with conventional a n a l o g u e c h e s t r a d i o g r a p h ( A R ) a m o n g pneumoconiotic patients and healthy controls. Thirty individuals consisting of 20 silica-exposed ex-workers and 10 healthy controls without occupational exposure to any mineral dust were examined with chest X-ray by AR, SR and FPD. Three occupational physicians, including one NIOSH B reader, assessed the digital and conventional radiographs by the side-by-side method according to the ILO 2000 International Classification of Radiograph of Pneumoconioses (ILO/ ICRP). No significant difference was shown between the subjective film qualities by AR and FPD. Interreader agreement of the profusion of small opacities on radiographs was high in the order of SR (κ=0.64), FPD (κ=0.62), and AR (κ=0.55). The profusions of small opacity for AR and FPD by the 12-point scaled profusion of ILO/ICRP did not show a statistically significant difference, but those for AR and SR showed a significant difference. The areas under the receiver operator curves (ROC) using clinical diagnosis by a pulmonologist as the reference showed no statistically significant difference among the three radiographic techniques. FPD gives image quality as good as that of AR, and it has acceptable agreement with AR in small profusion categories, which consequently assures its application to pneumoconiosis screening. SR showed less profusion than FPD and AR, which can be fixed with image modification. (J Occup Health 2007; 49: 39-45)

show abstract

Detection of CT-proved pulmonary nodules: comparison of selenium-based digital and conventional screen-film chest radiographs.

Abstract: In detecting pulmonary nodules, radiologists perform comparably with selenium-based digital and wide-latitude asymmetric screen-film radiographs.

Cited by 23 publications

References 0 publications

A Comparison of Computed Tomography, Computed Radiography, and Film‐screen Radiography for the Detection of Canine Pulmonary Nodules

A Comparison of Computed Tomography, Computed Radiography, and Film‐screen Radiography for the Detection of Canine Pulmonary Nodules

Pulmonary nodule detection with digital projection radiography: an ex-vivo study on increased latitude post-processing

A Flat‐Panel Detector Digital Radiography and a Storage Phosphor Computed Radiography: Screening for Pneumoconioses

Contact Info

Product

Resources

About