Detection of Biomedically Relevant Stilbenes from Wines by Mass Spectrometry

Andrei, Veronica; Copolovici, Dana; Munteanu, Florentina-Daniela; Wetie, Armand G. Ngounou; Mihai, Iuliana; Darie, Costel C.; Vasilescu, Alina

doi:10.1007/978-3-030-15950-4_40

Cited by 3 publications

(2 citation statements)

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“…Following the high interest generated by resveratrol in a lot of scientific areas, such as medicine, biology, chemistry, agriculture and food science, many analytical methods, principally based on chromatographic technique, have been developed for its quantification in biological or food matrices (Villamor et al 2013;Andrei et al 2014). Of course, since wine is a complex alcoholic beverage containing volatile and nonvolatile compounds, sample pre-treatment procedures were always necessary to simplify the matrix and make the sample suitable for instrumental analysis.…”

Section: Introductionmentioning

confidence: 99%

Determination of Trans-resveratrol in Wines, Spirits, and Grape Juices Using Solid-Phase Micro Extraction Coupled to Liquid Chromatography with UV Diode-Array Detection

et al. 2017

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Solid phase microextraction (polyacrylate fiber), coupled to liquid chromatography with UV-diode array detection, has been optimized for the determination of trans-resveratrol in in wines, spirits, and grape juices. The main aspects influencing fiber adsorption (fiber coating, extraction time, ethanol content, salt addition) and desorption (desorption and injection time, desorption solvent mixture composition, carryover) of the analyte have been investigated. The method permitted a fast and simple determination of free trans-resveratrol in commercial wines and spirits. It was found in all the analysed samples at concentration levels ranging from 0.007 to 4.486 µg mL -1 . Total transresveratrol concentrations were also evaluated after enzymatic deconjugation of piceid.

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Section: Introductionmentioning

confidence: 99%

Determination of Trans-resveratrol in Wines, Spirits, and Grape Juices Using Solid-Phase Micro Extraction Coupled to Liquid Chromatography with UV Diode-Array Detection

et al. 2017

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“…Recent advances in analytical chemistry based on mass spectrometry detection (Andrei, Ngounou Wetie, Mihai, Darie, & Vasilescu, ; Figueiredo‐González et al., ) are instrumental for the characterization of STBs in grapes/wine or in STB‐enriched supplements, to measure plasma levels of STBs and metabolites, and for the identification of novel biologically active STBs. To this respect, dihydro‐resveratrol derivatives were important metabolites detected after per‐oral RSV administration to the grey mouse lemur nonhuman primate (Menet et al., ).…”

Section: Bioavailability Of Stbsmentioning

confidence: 99%

Resveratrol and Related Stilbenoids, Nutraceutical/Dietary Complements with Health‐Promoting Actions: Industrial Production, Safety, and the Search for Mode of Action

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et al. 2018

Comp Rev Food Sci Food Safe

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This paper reviews the potential of stilbenoids as nutraceuticals. Stilbenoid compounds in wine are considered key factors in health-promoting benefits. Resveratrol and resveratrol-related compounds are found in a large diversity of vegetal products. The stilbene composition varies from wine to wine and from one season to another. Therefore, the article also reviews how food science and technology and wine industry may help in providing wines and/or food supplements with efficacious concentrations of stilbenes. The review also presents results from clinical trials and those derived from genomic/transcriptomic studies. The most studied stilbenoid, resveratrol, is a very safe compound. On the other hand, the potential benefits of stilbene intake are multiple and are apparently due to downregulation more than upregulation of gene expression. The field may take advantage from identifying the mechanism of action(s) and from providing useful data to show evidence for specific health benefits in a given tissue or for combating a given disease.

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