Abstract:BackgroundPemphigus is part of a group of blistering diseases that affect the skin and
mucous membranes. Based on its autoimmune origin, autoantibodies develop in
pemphigus that are directed toward cell surface components of keratinocytes.
However, some data cannot be explained, such as the lack of a relationship
between autoantibody levels and the severity of clinical manifestations,
treatment resistance, the presence of inflammatory infiltrates and the
potential occurrence of apoptosis as determinants of ves…
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