Detection, Occurrence and Fate of Emerging Contaminants in Agricultural Environments

Snow, Daniel D.; Cassada, David A.; Papastavros, Efthimia; Bartelt–hunt, Shannon L.; Li, Xu; Zhang, Yun; Zhang, Yuping; Qi, Yuan; Sallach, J. Brett

doi:10.2175/106143013x13698672321661

Cited by 4 publications

(1 citation statement)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The presence of these types of compounds is reported everywhere from river water to the drinking water at relatively higher concentration and reported to pose threats to aquatic and terrestrial organisms (Jones et al 2005;Kim et al 2007a;Stolker et al 2004;Ternes et al 2002). The two largest contributors of pharmaceuticals to the aquatic environment are believed to be from hospitals and households including both human and & Charuvila T. Aravindakumar cta@mgu.ac.in 1 animal excretion and drain disposal of pharmaceuticals (Asimakopoulos et al 2013;Cabeza et al 2012;Flores et al 2013;Liu et al 2011;Miege et al 2009;Snow et al 2012Snow et al , 2013. High-volume drugs are nonsteroidal anti-inflammatory drugs, cardiovascular drugs, central nervous system drugs, anticancer drugs, respiratory drugs, endocrinology drugs and antimicrobials (Khetan and Collins 2007).…”

Section: Introductionmentioning

confidence: 99%

Degradation of pharmaceuticals by ultrasound-based advanced oxidation process

2016

View full text Add to dashboard Cite

Water pollution by pharmaceutically active compounds is an emerging issue. Toxicological studies reveal that pharmaceuticals are indeed toxic for living organisms. The lack of suitable treatment technology for the complete removal of pharmaceuticals is therefore a major challenge. Advanced oxidation processes are emerging removal techniques that have many advantages versus conventional technologies. Many studies indicate that advanced oxidation processes, either in single or in combination with other degradation techniques, can enhance the degradation of pharmaceuticals in aqueous solutions. Here, we review the degradation of pharmaceuticals by sonolysis, an oxidation processes using ultrasound. In this technique, hydroxyl radicals are generated by pyrolytic cleavage of water molecules. We review the influence of operational parameters, additives and hybrid techniques on the degradation of pharmaceuticals. The maximum degradation of organic compounds was observed in the frequency range of 100-1000 kHz, which is in the high-frequency medium-power ultrasound. Even though almost all the experiments presented more than 90 % removal and good biodegradability of the target compound, good mineralization and the toxicity removal were hardly achieved. The efficiency of the degradation varies with water matrixes and varying pH. Major pathways of degradation are hydroxylation, dehalogenation, demethylation, decarboxylation, deamination, etc. More hybrid techniques have to be developed to scale up the application of ultrasound.

show abstract

Section: Introductionmentioning

confidence: 99%

Degradation of pharmaceuticals by ultrasound-based advanced oxidation process

2016

View full text Add to dashboard Cite

show abstract

A critical review of the environmental occurrence and potential effects in aquatic vertebrates of the potent androgen receptor agonist 17β‐trenbolone

Ankley

Coady

Gross³

et al. 2018

Enviro Toxic and Chemistry

View full text Add to dashboard Cite

Trenbolone acetate is widely used in some parts of the world for its desirable anabolic effects on livestock. Several metabolites of the acetate, including 17b-trenbolone, have been detected at low nanograms per liter concentrations in surface waters associated with animal feedlots. The 17b-trenbolone isomer can affect androgen receptor signaling pathways in various vertebrate species at comparatively low concentrations/doses. The present article provides a comprehensive review and synthesis of the existing literature concerning exposure to and biological effects of 17b-trenbolone, with an emphasis on potential risks to aquatic animals. In vitro studies indicate that, although 17b-trenbolone can activate several nuclear hormone receptors, its highest affinity is for the androgen receptor in all vertebrate taxa examined, including fish. Exposure of fish to nanograms per liter water concentrations of 17b-trenbolone can cause changes in endocrine function in the short term, and adverse apical effects in longer exposures during development and reproduction. Impacts on endocrine function typically are indicative of inappropriate androgen receptor signaling, such as changes in sex steroid metabolism, impacts on gonadal stage, and masculinization of females. Exposure of fish to 17b-trenbolone during sexual differentiation in early development can greatly skew sex ratios, whereas adult exposures can adversely impact fertility and fecundity. To fully assess ecosystem-level risks, additional research is warranted to address uncertainties as to the degree/breadth of environmental exposures and potential population-level effects of 17b-trenbolone in sensitive species.

show abstract

Development and validation of an analytical method based on liquid chromatography–tandem mass spectrometry detection for the simultaneous determination of 13 relevant wastewater-derived contaminants in lettuce

et al. 2017

View full text Add to dashboard Cite

We present an analytical method developed and validated to study the potential uptake of 13 selected drugs (ten pharmaceuticals, one illicit drug, and two transformation products) into lettuce plants from contaminated water and soil. Some of the selected drugs (i.e., cocaine, methadone, cis-diltiazem, valsartan, and valsartan acid), which are commonly present in treated wastewater, were investigated for the first time in plant tissues. The method is based on ultrasonic solvent extraction with acetonitrile-methanol (1:1, v/v) and subsequent automated extract cleanup and analysis by means of online solid-phase extraction-liquid chromatography-tandem mass spectrometry. Optimum extraction conditions were selected after evaluation of analyte recoveries with four different extraction techniques (ultrasonic solvent extraction, solid-liquid extraction, pressurized liquid extraction, and a "quick, easy, cheap, effective, rugged, and safe" based method) and six different solvent mixtures. Furthermore, two different solid-phase extraction cleanup sorbents were evaluated. The method developed has high sensitivity (with limits of detection between 0.1 and 12.6 ng per gram dry weight and limits of quantification between 0.5 and 42.0 ng per gram dry weight), satisfactory accuracy (with analyte relative recoveries above 80% for all analytes but acridone and oxcarbazepine), and good repeatability (with relative standard deviations below 9% for all analytes). As part of the validation procedure, the analytical method was applied to the analysis of lettuce plants irrigated with water fortified with the selected compounds for the entire growing period. The results obtained evidenced the transfer of all the investigated drugs into lettuce leaves. Graphical Abstract ᅟ.

show abstract

Detection, Occurrence and Fate of Emerging Contaminants in Agricultural Environments

Cited by 4 publications

References 31 publications

Degradation of pharmaceuticals by ultrasound-based advanced oxidation process

Degradation of pharmaceuticals by ultrasound-based advanced oxidation process

A critical review of the environmental occurrence and potential effects in aquatic vertebrates of the potent androgen receptor agonist 17β‐trenbolone

Development and validation of an analytical method based on liquid chromatography–tandem mass spectrometry detection for the simultaneous determination of 13 relevant wastewater-derived contaminants in lettuce

Contact Info

Product

Resources

About