Detection efficacy of analog [18F]FDG PET/CT, digital [18F]FDG, and [13N]NH3 PET/CT: a prospective, comparative study of patients with lung adenocarcinoma featuring ground glass nodules

Chen, Zhifeng; Long, Ya‐Qiu; Zhang, Yuying; Zhang, Bing; He, Qiao; Zhang, Xiangsong

doi:10.1007/s00330-022-09186-4

Cited by 6 publications

(1 citation statement)

References 41 publications

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“…Regarding evaluation of pediatric malignancies with half-dose 18 F-FDG protocols (1.85 MBq/kg), Chen et al [22] found that acquisition times as short as 1 min resulted in images of adequate diagnostic image quality with sufficient lesion detectability [23] which is imperative for pediatric patients undergoing frequent PET imaging during disease management. Furthermore, ultra-fast 30 s 18 F-FDG total-body PET imaging in 88 oncologic patients (3.7 MBq/kg) resulted in images with sufficient quality to meet clinical diagnostic requirements [24], although a clear reduction in image quality was seen for the 30 s images compared with the 300 s images.…”

Section: Overview Of Current Clinical Applicationsmentioning

confidence: 99%

Extending the clinical capabilities of short- and long-lived positron-emitting radionuclides through high sensitivity PET/CT

et al. 2022

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This review describes the main benefits of using long axial field of view (LAFOV) PET in clinical applications. As LAFOV PET is the latest development in PET instrumentation, many studies are ongoing that explore the potentials of these systems, which are characterized by ultra-high sensitivity. This review not only provides an overview of the published clinical applications using LAFOV PET so far, but also provides insight in clinical applications that are currently under investigation. Apart from the straightforward reduction in acquisition times or administered amount of radiotracer, LAFOV PET also allows for other clinical applications that to date were mostly limited to research, e.g., dual tracer imaging, whole body dynamic PET imaging, omission of CT in serial PET acquisition for repeat imaging, and studying molecular interactions between organ systems. It is expected that this generation of PET systems will significantly advance the field of nuclear medicine and molecular imaging.

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