Detection and risk factors of Coxiella burnetii infection in dairy cattle based on bulk tank milk samples in center of Iran

Nokhodian, Zary; Feizi, Awat; Moradi, Abdolreza; Yaran, Majid; Hoseini, Shervin Ghaffari; Ataei, Behrooz; Hosseini, Mona

doi:10.1016/j.prevetmed.2016.10.003

Cited by 16 publications

(11 citation statements)

References 21 publications

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“…This finding is consistent with the reported prevalence in other countries, confirming that C. burnetii shedding through milk is widespread in dairy cattle herds in different countries. Reports from other countries like the USA, the Netherlands, Spain, Hungary, Portugal, Iran, and Poland revealed a wide range of prevalence, reporting shedding of C. burnetii through cattle milk of between 18.8% and 94.3% [9,[28][29][30][31][32][33]. The reported C. burnetii prevalence of 33.7% in Greek dairy cattle is around the mid-range of the other countries, but still can be considered as high, since almost one out of three farms host active C. burnetii shedders.…”

Section: Discussionmentioning

confidence: 99%

Coxiella burnetii Shedding in Milk and Molecular Typing of Strains Infecting Dairy Cows in Greece

et al. 2021

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Ruminants are considered the commonest animal reservoir for human infection of Coxiella burnetii, the Q fever causative agent. Considering the recently described importance of human Q fever in Greece, we aimed at providing the first comprehensive direct evidence of C. burnetii in dairy cows in Greece, including the genetic characterization of strains. The 462 examined dairy farms represented all geographical areas of Greece. One bulk tank milk sample was collected from every farm and tested for the presence of C. burnetii. Molecular genotyping of strains, performed directly on samples, revealed the existence of two separate clades characterized by single nucleotide polymorphism (SNP) genotypes of type 1 and type 2. The two clades were clearly distinguished in multiple locus variable-number tandem repeat analysis (MLVA) by two discriminative loci: MS30 and MS28. Whereas MLVA profiles of SNP-type 2 clade were closely related to strains described in other European cattle populations, the MLVA profile observed within the SNP type 1 clade highlighted a peculiar genetic signature for Greece, related to genotypes found in sheep and goats in Europe. The shedding of C. burnetii bearing this genotype might have yet undefined human epidemiological consequences. Surveillance of the genetic distribution of C. burnetii from different sources is needed to fully understand the epidemiology of Q fever in Greece.

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Section: Discussionmentioning

confidence: 99%

Coxiella burnetii Shedding in Milk and Molecular Typing of Strains Infecting Dairy Cows in Greece

et al. 2021

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“…Regarding the risk factors for exposure of cattle to C. burnetii, significant associations have been primarily linked with management practices (Carbonero et al 2015, Nokhodian et al 2016, Boroduske et al 2017. In South Africa, the practice of communal kraaling at night may have contributed to the exposure of cattle to C. burnetii through milk, aerosol, and vectors.…”

Section: Discussionmentioning

confidence: 99%

Sero-Epidemiological Study of Selected Zoonotic and Abortifacient Pathogens in Cattle at a Wildlife-Livestock Interface in South Africa

Adesiyun

Knobel

Thompson

et al. 2020

Vector-Borne and Zoonotic Diseases

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A cross sectional sero-epidemiological study was conducted on cattle in a communal farming area adjacent to Kruger National Park at a wildlife-livestock interface in South Africa. A total of 184 cattle were screened for exposure to 5 abortifacient or zoonotic pathogens, namely Coxiella burnetii, Toxoplasma gondii, Chlamydophila abortus, Neospora caninum, and Rift Valley fever virus (RVFV) using enzyme-linked immunosorbent assays. In addition, the virus neutralization test was used to confirm the presence of antibodies to RVFV. The seroprevalence of C. burnetii, T. gondii, C. abortus, N. caninum, and RVFV antibodies was 38.0%, 32.6%, 20.7%, 1.6%, and 0.5%, respectively, and varied between locations (p < 0.001). Seroprevalence of C. burnetii and T. gondii was highly clustered by location (intraclass correlation coefficient [ICC] = 0.57), and that of C. abortus moderately so (ICC = 0.11). Seroprevalence was not associated with sex or age for any pathogen, except for C. abortus, for which seroprevalence was positively associated with age (p = 0.01). The predominant mixed infections were C. burnetii and T. gondii (15.2%) and C. burnetii, T. gondii, and C. abortus (13.0%). The serological detection of the five abortifacient pathogens in cattle indicates the potential for economic losses to livestock farmers, health impacts to domestic animals, transmission across the livestock-wildlife interface, and the risk of zoonotic transmission. This is the first documentation of T. gondii infection in cattle in South Africa, while exposure to C. burnetii, C. abortus, and N. caninum infections is being reported for the first time in cattle in a wildlife-livestock interface in the country.

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“…Because C. burnetii is an agent that can infect a wide range of hosts, from unicellular beings (such as amoeba) to invertebrates, reptiles, birds and mammals (CUTLER et al, 2007;NASPHV, 2013;ELDIN et al, 2017), the dispersion of this pathogen in extensive areas seems to be easily achieved. In this sense, the data presented in this study were relevant, both from an economic point of view and for public health, considering that cattle are one of the main reservoirs for human infection (GEORGIEV et al, 2013;NOKHODIAN et al, 2016). An outbreak of Q fever has been recently described among cadets in the state of Rio de Janeiro, Southeastern Brazil, whose diagnosis was confirmed by serologic tests (LEMOS et al, 2018).…”

Section: Discussionmentioning

confidence: 74%

“…Although serological evidence of exposure to C. burnetii has already been reported in cattle in Europe (CZAPLICKI et al, 2009;AGGER et al, 2010;BOTTCHER et al, 2011;GACHE et al, 2017;RYAN et al, 2018;VARELA-CASTRO et al, 2018;VIDAL et al, 2017;SOFTIC et al, 2018), Asia (CETINKAYA et al, 2000NOKHODIAN et al, 2016), North America (MCQUISTON et al, 2005 and Africa (KAMGA-WALADJO et al, 2010;SCOLAMACCHIA et al, 2010), there are few data on seroprevalence to this agent in ruminants in Brazil. In this regard, while Guimarães et al (2017) found a seropositivity rate of 2% for C. burnetii among sheep sampled in the state of Piauí, northeast of Brazil, Oliveira et al (2018) found a seroprevalence of 55.1% in a herd of goats with history of reproductive disorders in the state of Alagoas, Northeast of Brazil.…”

Section: Discussionmentioning

confidence: 99%

Coxiella burnetii associated with BVDV (Bovine Viral Diarrhea Virus), BoHV (Bovine Herpesvirus), Leptospira spp., Neospora caninum, Toxoplasma gondii and Trypanosoma vivax in reproductive disorders in cattle

Zanatto

Gatto

Labruna

et al. 2019

Rev. Bras. Parasitol. Vet.

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This is a cross-sectional study to assess the presence of antibodies in ruminants against selected pathogens associated with reproductive disorders in cattle in four Brazilian states, including the zoonotic agent Coxiella burnetii. The used tests were Virus Neutralization Assay for IBR and BVD, Microscopic Agglutination Test for Leptospira spp., Indirect Fluorescent Antibody Test (IFAT) for C. burnetii and Toxoplasma gondii, and Enzyme-Linked Immunosorbent Assay for Neospora caninum and Trypanosoma vivax. Seropositivity for C. burnetii was 13.7% with titers from 128 to 131,072; 57.8% for BoHV-1, with titers between 2 and 1,024; 47.1% for BVDV-1a, with titers from 10 to 5,120; 89.2% for N. caninum; 50% for T. vivax; and 52.0% for Leptospira spp., with titers between 100 to 800 (the following serovars were found: Tarassovi, Grippotyphosa, Canicola, Copenhageni, Wolffi, Hardjo, Pomona and Icterohaemorrhagiae); 19.6% for T. gondii with titer of 40. This is the first study that has identified C. burnetii in cattle associated with BoHV and BVDV, N. caninum, Leptospira spp., T. gondii and T. vivax. Thus, future studies should be conducted to investigate how widespread this pathogen is in Brazilian cattle herds.

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Detection and risk factors of Coxiella burnetii infection in dairy cattle based on bulk tank milk samples in center of Iran

Cited by 16 publications

References 21 publications

Coxiella burnetii Shedding in Milk and Molecular Typing of Strains Infecting Dairy Cows in Greece

Coxiella burnetii Shedding in Milk and Molecular Typing of Strains Infecting Dairy Cows in Greece

Sero-Epidemiological Study of Selected Zoonotic and Abortifacient Pathogens in Cattle at a Wildlife-Livestock Interface in South Africa

Coxiella burnetii associated with BVDV (Bovine Viral Diarrhea Virus), BoHV (Bovine Herpesvirus), Leptospira spp., Neospora caninum, Toxoplasma gondii and Trypanosoma vivax in reproductive disorders in cattle

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