Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central‐Southern Italy

Amoroso, Maria Grazia; Russo, Danilo; Lanave, Gianvito; Cistrone, Luca; Pratelli, Annamaria; Martella, Vito; Decaro, Nicola; Fusco, Giovanna

doi:10.1111/zph.12484

Cited by 16 publications

(12 citation statements)

References 65 publications

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“…Coronavirus RNA was detected in three out of 27 faecal samples: 11%, close to previously reported frequency [10], less than that observed in other studies [17,30], unlike results obtained in central-southern Italy [33]. Positive samples were collected in different locations of northern and central Sardinia from three different bat species: the greater horseshoe bat (Rhinolophus ferrumequinum), the brown long-eared bat (Plecotus auritus), and the European free-tailed bat (Tadarida teniotis).…”

Section: Resultssupporting

confidence: 55%

Molecular identification of Betacoronavirus in bats from Sardinia (Italy): first detection and phylogeny

Lecis

Mucedda²,

Pidinchedda³

et al. 2018

Virus Genes

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Bats may be natural reservoirs for a large variety of emerging viruses, including mammalian coronaviruses (CoV). The recent emergence of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) in humans, with evidence that these viruses may have their ancestry in bats, highlights the importance of virus surveillance in bat populations. Here, we report the identification and molecular characterization of a bat β-Coronavirus, detected during a viral survey carried out on different bat species in the island of Sardinia (Italy). Cutaneous, oral swabs, and faecal samples were collected from 46 bats, belonging to 15 different species, and tested for viral presence. Coronavirus RNA was detected in faecal samples from three different species: the greater horseshoe bat (Rhinolophus ferrumequinum), the brown long-eared bat (Plecotus auritus), and the European free-tailed bat (Tadarida teniotis). Phylogenetic analyses based on RNA-dependent RNA polymerase (RdRp) sequences assigned the detected CoV to clade 2b within betacoronaviruses, clustering with SARS-like bat CoVs previously reported. These findings point to the need for continued surveillance of bat CoV circulating in Sardinian bats, and extend the current knowledge on CoV ecology with novel sequences detected in bat species not previously described as β-Coronavirus hosts.

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Section: Resultssupporting

confidence: 55%

Molecular identification of Betacoronavirus in bats from Sardinia (Italy): first detection and phylogeny

Lecis

Mucedda²,

Pidinchedda³

et al. 2018

Virus Genes

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“…Virological surveillance of bat populations in Italy is a relative novelty and has only recently been extensively applied, but almost immediately, a great heterogeneity of virus identifications has been observed. Viruses belonging to several viral families, such as Reoviridae [14], Coronaviridae [15,20,21,22,23,24], Paramyxoviridae [24], Rhabdoviridae [16,25], and Astroviridae [26], have been detected, allowing the identification of some novel/previously unknown viral agents. The results of the general surveillance of bats, which have been randomly applied so far as pilot virus discovery studies, may drive future activity to more specific longitudinal and target studies aimed at understanding the epidemiology of potential new pathogens.…”

Section: Discussionmentioning

confidence: 99%

Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy

Lelli

Llombart‐Bosch

Prosperi

et al. 2019

Viruses

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Interest in bat-related viruses has increased considerably during the last decade, leading to the discovery of a rising number of new viruses in several bat species. Poxviridae are a large, diverse family of DNA viruses that can infect a wide range of vertebrates and invertebrates. To date, only a few documented detections of poxviruses have been described in bat populations on three different continents (America, Africa, and Australia). These viruses are phylogenetically dissimilar and have diverse clinical impacts on their hosts. Herein, we report the isolation, nearly complete genome sequencing, and annotation of a novel poxvirus detected from an insectivorous bat (Hypsugo savii) in Northern Italy. The virus is tentatively named Hypsugopoxvirus (HYPV) after the bat species from which it was isolated. The nearly complete genome size is 166,600 nt and it encodes 161 genes. Genome analyses suggest that HYPV belongs to the Chordopoxvirinae subfamily, with the highest nucleotide identity (85%) to Eptesipoxvirus (EPTV) detected from a microbat Eptesicus fuscus in WA, USA, in 2011. To date, HYPV represents the first poxvirus detected in bats in Europe; thus, its viral ecology and disease associations should be investigated further.

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“…We have read with interest the manuscript by Maria Grazia Amoroso et al, which provides an interesting and potentially important perspective into astrovirus infections in insectivorous bats from Central and Southern Italy (Amoroso et al, 2018).…”

Section: Comments To "Detection and Phylogenetic Characterization Of mentioning

confidence: 97%

Comments to “Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central‐Southern Italy”

Benedictis

Bourhy

Echevarrı́a

et al. 2019

Zoonoses and Public Health

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Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central‐Southern Italy

Cited by 16 publications

References 65 publications

Molecular identification of Betacoronavirus in bats from Sardinia (Italy): first detection and phylogeny

Molecular identification of Betacoronavirus in bats from Sardinia (Italy): first detection and phylogeny

Hypsugopoxvirus: A Novel Poxvirus Isolated from Hypsugo savii in Italy

Comments to “Detection and phylogenetic characterization of astroviruses in insectivorous bats from Central‐Southern Italy”

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