Detection and Monitoring of Human Herpesvirus 7 in Adult Liver Transplant Patients: Impact on Clinical Course and Association With Cytomegalovirus

Cytomegalovirus Infection in Liver Transplantation

“…Detection of N-PCR and antigenemia are useful markers for active infection [30,31].The rates of CMV found in our groups are similar to other services [24,25,[30][31][32].…”

“…CMV is frequently detected in our patients after liver transplantation [24,25,30,31]. Detection of N-PCR and antigenemia are useful markers for active infection [30,31].The rates of CMV found in our groups are similar to other services [24,25,[30][31][32].…”

“…The clinical course of CMV in immunocompetent individuals may be asymptomatic or may resemble "Mononucleosis Syndrome" presented by persistent fever, myalgia, pharyngitis, lymphadenopathy, sweating and hepatosplenomegaly [10,[28][29][30][31][32][33][34].…”

“…Early diagnosis is important as early treatment of asymptomatic active infection reduces morbidity [24,31,46,47]. The first method of diagnosis used to identify the CMV was exfoliative cytology.…”

“…False negative results can also occur due to presence of inhibitors in the sample [55,60]. The sample type and method of extracting DNA from these samples must be carefully chosen to avoid this [31,61].…”