Detection and localization onDrosophila melanogaster polytene chromosomes of sequences homologous to oncogeneyes

Samant, Sadhana; Deobagkar, Deepti D.; Godbole, N. N.; Deobagkar, Dileep N.

doi:10.1007/bf02927853

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C-yes Expression Patterns: Comparison and Contrast With C-src1

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2003

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“…Phylogenetically, c-Yes expression has been confirmed in simple vertebrates such as Xenopus (25) and teleost fish (26). Although there is a single report of a c-Yes homolog in drosophila (27), this observation was not verified. The potential absence of c-Yes from Drosophila is interesting given that there is a c-Src ortholog present in fly (28)(29)(30).…”

Section: C-yes Expression Patterns: Comparison and Contrast With C-srcmentioning

confidence: 88%

Specificity in signaling by c-Yes

Flynn¹

2003

Front Biosci

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c-Yes and c-Src are the two most closely related members of the Src family of nonreceptor tyrosine kinases. Although there is much evidence to support redundancy in signaling between these two kinases, there is also a growing body of evidence to indicate specificity in signaling. In this review, we summarize c-Yes, its potential functions and its ability to modulate signals that are distinct from c-Src.

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Section: C-yes Expression Patterns: Comparison and Contrast With C-srcmentioning

confidence: 88%