Detection and extraction of heavy metal ions using paper-based analytical devices fabricated via atom stamp printing

Guan, Yanfang; Sun, Baichuan

doi:10.1038/s41378-019-0123-9

Cited by 47 publications

(30 citation statements)

References 47 publications

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“…In addition to the positive charge of PEI, the deprotonated forms of CA were also pH-dependent (pKa 1 = 3.39; pKa 2 = 5.78; pKa 3 = 8.35 [ 56 ]), which could suggest that the deprotonated state of CA promotes the binding interaction of CA to PEI. Third, the detection channel’s width refers to the area available for the complex formation of PEI immobilized on the membrane and free CA [ 57 ]. This factor affects the slope of the linear regression line.…”

Section: Discussionmentioning

confidence: 99%

A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices

et al. 2021

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A simple and rapid distance paper-based analytical device (dPAD) for the detection of lead (Pb) in foods is proposed herein. The assay principle is based on competitive binding between carminic acid (CA) and polyethyleneimine (PEI) to Pb in a food sample. The paper channels were pre-immobilized with PEI, before reacting with a mixture of the sample and CA. Pb can strongly bind to the CA; hence, the length of the red color deposition on the flow channel decreased as a lower amount of free CA bound to PEI. The dPAD exhibited good linear correlation, with ranges of 5–100 µg·mL−1 (R2 = 0.974) of Pb. Although, the limit of detection (LOD) of this platform was rather high, at 12.3 µg·mL−1, a series of standard additions (8.0, 9.0, and 10.0 µg·mL−1) can be used to interpret the cutoff of Pb concentrations at higher or lower than 2 µg·mL−1. The presence of common metal ions such as calcium, magnesium, nickel, and zinc did not interfere with the color distance readout. The validity of the developed dPAD was demonstrated by its applicability to screen the contamination of Pb in century egg samples. The results obtained from the dPAD are in accordance with the concentration measured by atomic absorption spectroscopy (AAS) (n = 9). In conclusion, this proposed dPAD, combined with the standard addition method, could be applied for screening Pb contamination in food matrices. This platform is, therefore, potentially applicable for field measurements of Pb in developing countries, because it is cheap and rapid, and it requires no significant laborious instruments.

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Section: Discussionmentioning

confidence: 99%

A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices

et al. 2021

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“…In the detection process, the extraction step always requires separation of the target analyte (e.g., cells, virus, ions, proteins, DNA, drugs, RNA, and so on) from the collected sample (e.g., biological, environmental, or food) for subsequent measurement and analysis. Many paper devices have been proposed for sample extraction [58][59][60][61][62][63][64][65][66][67][68], including commercial FTA and FTA elute cards [41,43]. However, while these cards are easy to use, their integration with lab-on-paper platforms still presents a significant challenge.…”

Section: Sample Extractionmentioning

confidence: 99%

“…However, while these cards are easy to use, their integration with lab-on-paper platforms still presents a significant challenge. Accordingly, many studies have attempted to implement the extraction function on the paper platform itself extraction device of lab-on-paper can be used for DNA, RNA, dug, heavy metal ions, and pesticide residues, and so on [61][62][63][64][65][66][67][68]. For instance, Batule et al [63] presented a lab-on-paper platform based on nucleic acid testing for the rapid extraction and detection of virus RNA from blood serum samples.…”

Section: Sample Extractionmentioning

confidence: 99%

“…Moreover, the detection results obtained for the MAU content of urine samples collected from real diabetic patients were found to be in excellent agreement with those obtained using a traditional immunoturbidimetry method. and pesticide residues, and so on [61][62][63][64][65][66][67][68]. For instance, Batule et al [63] presented a labon-paper platform based on nucleic acid testing for the rapid extraction and detection of virus RNA from blood serum samples.…”

Section: Sample Concentration/amplificationmentioning

confidence: 99%

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Lab-on-Paper Devices for Diagnosis of Human Diseases Using Urine Samples—A Review

et al. 2021

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In recent years, microfluidic lab-on-paper devices have emerged as a rapid and low-cost alternative to traditional laboratory tests. Additionally, they were widely considered as a promising solution for point-of-care testing (POCT) at home or regions that lack medical infrastructure and resources. This review describes important advances in microfluidic lab-on-paper diagnostics for human health monitoring and disease diagnosis over the past five years. The review commenced by explaining the choice of paper, fabrication methods, and detection techniques to realize microfluidic lab-on-paper devices. Then, the sample pretreatment procedure used to improve the detection performance of lab-on-paper devices was introduced. Furthermore, an in-depth review of lab-on-paper devices for disease measurement based on an analysis of urine samples was presented. The review concludes with the potential challenges that the future development of commercial microfluidic lab-on-paper platforms for human disease detection would face.

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“…It has the potential to be widely adopted for point of care applications, particularly in resource-poor settings 11 . But the major drawback of this method is its poor sensitivity to detect low concentrations (μg L −1 ) of the target analyte 12 .…”

Section: Introductionmentioning

confidence: 99%

Adsorptive colorimetric determination of chromium(VI) ions at ultratrace levels using amine functionalized mesoporous silica

Ghosh

Gopalakrishnan

Renganathan

et al. 2022

Sci Rep

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There is an urgent need for a rapid, affordable and sensitive analytical method for periodic monitoring of heavy metals in water bodies. Herein, we report for the first time a versatile method for ultratrace level metal detection based on colorimetric sensing. The method integrates preconcentration using a nanomaterial with a colorimetric assay performed directly on the metal-enriched nanomaterial surface. This method circumvents the need for tedious sample pre-processing steps and the complex development of colorimetric probes, thereby reducing the complexity of the analytical procedure. The efficacy of the proposed method was demonstrated for chromium(VI) ions detection in water samples. Amine functionalized mesoporous silica (AMS) obtained from a one-pot synthesis was utilized as a pre-concentration material. The structural and chemical analysis of AMS was conducted to confirm its physico-chemical properties. The pre-concentration conditions were optimized to maximise the colorimetric signal. AMS exhibited a discernible colour change from white to purple (visible to the naked eye) for trace Cr(VI) ions concentration as low as 0.5 μg L−1. This method shows high selectivity for Cr(VI) ions with no colorimetric signal from other metal ions. We believe our method of analysis has a high scope for de-centralized monitoring of organic/inorganic pollutants in resource-constrained settings.

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Detection and extraction of heavy metal ions using paper-based analytical devices fabricated via atom stamp printing

Cited by 47 publications

References 47 publications

A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices

A Simple Distance Paper-Based Analytical Device for the Screening of Lead in Food Matrices

Lab-on-Paper Devices for Diagnosis of Human Diseases Using Urine Samples—A Review

Adsorptive colorimetric determination of chromium(VI) ions at ultratrace levels using amine functionalized mesoporous silica

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