The Sun shines down on the Earth breathing life into everything around us. A myriad of other stars likewise illuminate their own neighborhoods. However, those distant stars are often much less benevolent to their local environments than the Sun is to its own back yard. The sum of these stellar illuminations is the interstellar radiation field (ISRF), which is made up of photons originating from a large number of stars with very different colors, activity levels, and ages. One should, of course, add the extragalactic and cosmological contributions to this radiation.The photons of the ISRF are responsible for warming the cold interstellar medium through the heating of the gas and dust. They can, when particularly energetic, lead to the destruction of that gas and dust by "photo-dissociation". Some important effects of the ISRF on the interstellar medium include the heating of the gas by the energetic photo-electrons ejected from grains following ultraviolet photon absorption, the forces exerted on dust by photons that then drive mass movements, and the thermal energy re-radiated by dust at mid-infrared to millimeter wavelengths that can heat dust in the interiors of dense cores that are opaque to stellar visible and ultraviolet photons.A detailed knowledge of the combined contribution of the stars to the ISRF is one of the keys to interstellar medium studies of the gas and dust physics. Earlier ISRF studies mainly focused on the shorter wavelength, stellar part of the ISRF (e.g. Habing 1968; Draine 1978, online). John Mathis, Peter Mezger, and Nino Panagia built upon these foundations in their 1983 paper, which was itself based on the soon-to-be eclipsed companion paper (Mezger et al. 1982, with >200 citations), and laid out a four-component stellar radiation field model and an associated dust emission model to explain the existing observations of the ISRF from the ultraviolet to the mm wavelength domain. The utility of their approach has clearly been attested to over the years by the almost 600 SAO/NASA Astrophysics Data System (ADS) citations to the paper. This is a seminal piece of work in the many areas of interstellar medium physics that it tackles, including the stellar input to the ISRF, the dust heating in GMCs and dense cloud interiors, and radiative transfer effects in interstellar clouds. The scope of the paper couples some of the extremes of astrophysics, i.e., encompassing studies of the big (stars) and the small (dust grains), and leads the reader to a series of analytical equations that provide a complete and self-consistent description of the ISRF and the dust temperatures in the interstellar medium.An important element that this work brought to interstellar medium studies was the calculation of the three-dimensional variations in the Galactic ISRF, principally as a function of galacto-centric distance (D G ). This was based on a simple geometric model of the Galaxy, omitting spiral structure and the clumpiness of the ISM. In particular, Mathis, Mezger, and Panagia showed that the ISRF total energ...