1986
DOI: 10.1007/978-3-642-70664-6_13
|View full text |Cite
|
Sign up to set email alerts
|

Detection and Biochemistry of Cell Surface Protein Kinase

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
4
0

Year Published

1989
1989
2001
2001

Publication Types

Select...
5
1

Relationship

0
6

Authors

Journals

citations
Cited by 7 publications
(4 citation statements)
references
References 23 publications
0
4
0
Order By: Relevance
“…The specificity for ATP and the selectivity for 3T6 cells indicate, that external ATP interact with specific sites on the cell surface. These sites could be enzymes or receptors (Weisman et al, 1988;Gordon, 1986;Kinzel et al, 1986;Kubler et al, 1986;Burnstock and Kennedy, 1985;Williams, 1987) Exogenous adenine nucleotides serve as substrates for cell surface nucleotidases, which catalyze their hydrolysis to adenosine. Adenosine was found to inhibit the growth of several cell lines (Henderson and Scott, 1981;Fox and Kelley, 1978;Ishii and Green, 19731, but the proliferation of 3T6 cells is not inhibited upon addition of adenosine, up to 1 mM (Weisman et al, 1988).…”
Section: Discussionmentioning
confidence: 99%
“…The specificity for ATP and the selectivity for 3T6 cells indicate, that external ATP interact with specific sites on the cell surface. These sites could be enzymes or receptors (Weisman et al, 1988;Gordon, 1986;Kinzel et al, 1986;Kubler et al, 1986;Burnstock and Kennedy, 1985;Williams, 1987) Exogenous adenine nucleotides serve as substrates for cell surface nucleotidases, which catalyze their hydrolysis to adenosine. Adenosine was found to inhibit the growth of several cell lines (Henderson and Scott, 1981;Fox and Kelley, 1978;Ishii and Green, 19731, but the proliferation of 3T6 cells is not inhibited upon addition of adenosine, up to 1 mM (Weisman et al, 1988).…”
Section: Discussionmentioning
confidence: 99%
“…Cell viability was evaluated by a number of independent criteria, as described previously [2][3][4][5].…”
Section: Figure 1 Cell-surface Protein Phosphorylation By Ecto-pkmentioning
confidence: 99%
“…Cell-surface (ecto-) protein kinase (PK) activities enable cells to phosphorylate membrane-bound substrates and suitable extracellular molecules ; these, in turn, have been shown to connect with important functions for the regulation of cellular development and cell-environment interactions [1]. Using intact cells for assaying ecto-PK activities [2][3][4][5], we found that a large range of proliferating and post-mitotic cell types carry serine\threonine ecto-PK with distinct substrate specificity, notably of the constitutively active CK2 (protein formerly known as casein kinase 2) and CK1 types [2,6], and cAMP-dependent PK [7].…”
Section: Introductionmentioning
confidence: 99%
“…Another possible function of extracellular ATP is its property to serve as a substrate of ecto-proteinkinases, which have been detected on several cells of different origin [74]. Human neutrophils [37] and erythrocytes [75] also carry such an ectoenzyme on their cell surfaces.…”
Section: Effects and Target Cellsmentioning
confidence: 99%