The 690 km 2 Tacámbaro-Puruarán area located at the arc-front part of the Michoácan-Guanajuato volcanic field in the Trans-Mexican Volcanic Belt (TMVB) records a protracted history of volcanism that culminated with intense monogenetic activity in the Holocene. Geologic mapping, 40 Ar/ 39 Ar and 14 C radiometric dating, and whole-rock chemical analyses of volcanic products provide insights to that history. Eocene volcanics (55-40 Ma) exposed at uplifted blocks are related to a magmatic arc that preceded the TMVB. Early TMVB products are represented by poorly exposed Pliocene silicic domes (5-2 Ma). Quaternary (<2 Ma) volcanoes (114 mapped) are mainly scoria cones with lavas (49 vol.%), viscous lava flows (22 vol.%), and lava shields (22 vol.%). Erupted products are dominantly either basaltic andesites (37 vol. %), or andesites (17 vol.%), or span across both compositions (28 vol.%). Basalts (9 vol.%), dacites (4 vol.%), shoshonites (2 vol.%), and other alkali-rich rocks (<3 vol.%) occur subordinately. Early-Pleistocene volcanism was bimodal (dacites and basalts) and voluminous while since 1 Ma smallvolume eruptions of intermediate magmas have dominated.Higher rates of lithospheric extension in the Quaternary may have allowed a larger number of small, poorly evolved dikes to reach the surface during this period. Eruptive centers as old as 1.7 Ma are aligned in a NE direction parallel to both, basement faults and the direction of regional compressive stress, implying structural control on volcanic activity. Data suggest that volcanism was strongly pulsatory and fed by localized lowdegree partial melting of mantle sources. In the Holocene, at least 13 eruptions occurred (average recurrence interval of 800 years). These produced~3.8 km 3 of basaltic andesitic to andesitic magma and included four eruptions dated at~1,000; 4,000; 8,000; and 11,000 years BC (calibrated 14 C ages). To date, this is one of the highest monogenetic eruption frequencies detected within such a small area in a subduction-related arc-setting. These anomalous rates of monogenetic activity in an area with thick crust (>30 km) may be related to high rates of magma production at depth and a favorable tectonic setting.