Abstract:New sequencing technologies have opened the door to many new research
opportunities, but these advances in data collection are not always
compatible with some important methods for data analysis. Fis has been a
staple calculation in the field of population genetics. Fis can be used
to measure either a departure from random mating, or measure underlying
selective pressures for or against heterozygote genotypes. However, when
using Next Generation Sequencing (NGS) technology on multi-locus gene
families it is of… Show more
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