2020
DOI: 10.23937/2643-461x/1710037
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Detecting Mycobacterium ulcerans in Clinical Specimens from Ghana: Comparative Evaluation of BU-LAMP and IS2404 PCR

Abstract: Background: Conventional and nested polymerase chain reaction (PCR), and loop-mediated isothermal amplification (LAMP) have been used to identify Mycobacterium ulcerans in separate studies and different specimens. However, the sensitivities of these three techniques have not been compared in a single study. Objective: This study compared the performance of two variant PCR techniques and LAMP assays to detect M. Ulcerans in same clinical specimens. Methods: Samples were collected from patients suspected of Buru… Show more

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