Detecting and tracking bacteria with quantum light

Spedalieri, Gaetana; Piersimoni, Lolita; Laurino, Omar; Braunstein, Samuel L.; Pirandola, Stefano

doi:10.1103/physrevresearch.2.043260

Cited by 13 publications

(11 citation statements)

References 17 publications

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“…The QCR bound for the estimation uncertainty Var(Γ − ) can thus be written in terms of Eqs. (34) and (35) as…”

Section: Twin-beam Inputmentioning

confidence: 99%

“…Both experimental studies clearly demonstrated the quantum enhancement in the estimation precision, i.e., sub-shot-noise limited sensing performance has been observed. Although schemes using quantum light emerge as a tool for ultimate sensing technology from diverse perspectives [32][33][34], sub-shot-noise limited quantum schemes for CD sensing have not yet been studied.…”

Section: Introductionmentioning

confidence: 99%

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Optimal circular dichroism sensing with quantum light: Multiparameter estimation approach

et al. 2021

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The measurement of circular dichroism (CD) has widely been exploited to distinguish the different enantiomers of chiral structures. It has been applied to natural materials (e.g. molecules) as well as to artificial materials (e.g. nanophotonic structures). However, especially for chiral molecules the signal level is very low and increasing the signal-to-noise ratio is of paramount importance to either shorten the necessary measurement time or to lower the minimum detectable molecule concentration. As one solution to this problem, we propose here to use quantum states of light in CD sensing to reduce the noise below the shot noise limit that is encountered when using coherent states of light. Through a multi-parameter estimation approach, we identify the ultimate quantum limit to precision of CD sensing, allowing for general schemes including additional ancillary modes. We show that the ultimate quantum limit can be achieved by various optimal schemes. It includes not only Fock state input in direct sensing configuration but also twin-beam input in ancilla-assisted sensing configuration, for both of which photon number resolving detection needs to be performed as the optimal measurement setting. These optimal schemes offer a significant quantum enhancement even in the presence of additional system loss. The optimality of a practical scheme using a twin-beam state in direct sensing configuration is also investigated in details as a nearly optimal scheme for CD sensing when the actual CD signal is very small. Alternative schemes involving single-photon sources and detectors are also proposed. This work paves the way for further investigations of quantum metrological techniques in chirality sensing.

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“…The QCR bound for the estimation uncertainty Var(Γ − ) can thus be written in terms of Eqs. (34) and (35) as…”

Section: Twin-beam Inputmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Optimal circular dichroism sensing with quantum light: Multiparameter estimation approach

et al. 2021

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“…One can check that, for other regimes of parameters, the presence of squeezing can strictly outperform coherent states even if the advantage can be very small. As we discuss below the difference becomes more appreciable in problems of quantum reading [9] or short-range quantum scanning [18], where the transmissivities associated with the hypotheses are relatively high.…”

Section: Optimized Probes For Target Detectionmentioning

confidence: 99%

“…This scenario can refer to the readout of an optical cell with two different reflectivities [9], or to the scan of a biological sample to distinguish between a blank from a contaminated sample [18]. For our numerical investigation, we consider high transmissivities η 0 = 0.9 and η 1 = 0.98, and relativelyhigh signal energy nS = 1.…”

Section: Optimized Probes For Quantum Reading or Scanningmentioning

confidence: 99%

Optimal squeezing for quantum target detection

Spedalieri,

Pirandola

2021

Preprint

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It is believed that the optimal performance of a quantum lidar or radar in the absence of an idler and only using Gaussian resources cannot exceed the performance of a semiclassical setup based on coherent states and homodyne detection. Here we disprove this conjecture by showing that an idlerfree squeezed-based setup can beat this benchmark. More generally, we show that probes whose displacement and squeezing are jointly optimized can strictly outperform coherent states with the same mean number of input photons for both the problems of quantum illumination and reading.

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“…Quantum metrology exploits quantum mechanical resources, such as entanglement and squeezing, to measure a physical parameter with higher resolution than any strategy with classical resources. Many quantum metrology protocols in the photonic regime [1] have been proposed such as quantum illumination (QI) [2][3][4][5], quantum enhanced position and velocity estimation [6][7][8][9][10][11][12], quantum phase estimation [13,14], transmission parameter estimation [15][16][17][18][19], noise estimation [20], and estimation of separation between objects [21,22], among others. In these protocols, information about an object is retrieved by interrogating it with a signal beam.…”

Section: Introductionmentioning

confidence: 99%