Détecter et traiter les troubles comorbides aux premiers épisodes psychotiques : un levier pour le rétablissement

Corbeil, Olivier; Bérubé, Félix‐Antoine; Artaud, Laurence; Roy, Marc‐André

doi:10.7202/1088187ar

Cited by 4 publications

(13 citation statements)

References 41 publications

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“…In practice, many clinicians are hesitant to prescribe stimulants in individuals with a primary psychotic disorder due to concerns of a potential worsening of positive symptoms and the risk of misuse. Two papers discussed the management of comorbid ADHD and early phase psychosis [ 16 , 19 ].…”

Section: Resultsmentioning

confidence: 99%

“…The authors found that the prevalence of ADHD in adolescents and young adults with FEP ranged from 8.1% to 24% [ 16 ]. In detecting comorbid ADHD and FEP, the authors suggest that ADHD screening should be based on a rigorous developmental history and neuropsychological evaluation [ 16 ]. For treatment, the authors suggest treatment with an antipsychotic as the psychotic disorder can contribute to and mimic symptoms of ADHD [ 16 ].…”

Section: Resultsmentioning

confidence: 99%

“…Any disagreements between reviewers were discussed and resolved by reaching a consensus. A total of 22 studies were then included for review [ 7 , 8 , 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. Please see Figure 1 of the schematic outlining our screening process.…”

Section: Methodsmentioning

confidence: 99%

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A Narrative Review Exploring Attention Deficit/Hyperactivity Disorder in Patients with Early Psychosis

Toba-Oluboka,

Dempster

2024

Brain Sciences

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While both Attention deficit hyperactivity disorder (ADHD) and schizophrenia are considered to have neurodevelopmental origins with associated impairments in executive functioning, there is a paucity of clinical guidelines pertaining specifically to this comorbidity. We sought to summarize the existing literature on ADHD in early psychosis patients, focusing on issues that would be most relevant to clinical practice. For this narrative review, we completed a search on PubMed and PsycINFO with 22 papers meeting criteria for review. Overall, it appears that a diagnosis of ADHD in childhood increases the risk of the subsequent development of a primary psychotic disorder. This risk may be modified by higher rates of substance use and could be related to shared premorbid risk factors for both conditions, such as obstetrical complications. Stimulant use has been associated with the onset of psychotic symptoms in some individuals, but it is unclear whether certain subgroups are more susceptible. Despite the fact that these two conditions co-occur relatively frequently, there is currently a lack of objective diagnostic tests for ADHD specific to populations with primary psychotic disorders, and a paucity of evidence on whether stimulants are effective for ADHD symptoms in this sub-group. Future research is warranted to investigate whether stimulant treatment confers any additional risks for symptom exacerbation in individuals with primary psychotic disorders taking antipsychotic maintenance treatment.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

A Narrative Review Exploring Attention Deficit/Hyperactivity Disorder in Patients with Early Psychosis

Toba-Oluboka,

Dempster

2024

Brain Sciences

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“…[13][14][15] Hence, it becomes imperative to adopt a comprehensive approach to recovery that addresses these interconnected challenges. [16][17][18][19][20] Pathological gambling, now termed gambling disorder, was previously categorized as an impulse-control disorder in earlier iterations of the Diagnostic and Statistical Manual of Mental Disorders (DSM). 21,22 However, in 2013, the DSM-5 rather classified gambling disorder as a behavioral addiction based on evidence highlighting many similarities with substance use disorders, particularly with regards to symptom presentation, genetic predisposition, and neurobiological correlates.…”

Section: Introductionmentioning

confidence: 99%

“…In addition to negative and cognitive symptoms that are less responsive to treatment than positive symptoms, the frequent co‐occurrence of other psychiatric conditions, such as substance use disorders may partly explain difficulties to fully achieve critical facets of recovery, including social, occupational, and vocational functioning 13–15 . Hence, it becomes imperative to adopt a comprehensive approach to recovery that addresses these interconnected challenges 16–20 …”

Section: Introductionmentioning

confidence: 99%

Problem gambling in psychotic disorders: A systematic review and meta‐analysis of prevalence

Corbeil,

Anderson,

Béchard

et al. 2024

Acta Psychiatr Scand

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IntroductionProblem gambling (PBG) is more common in people with mental health disorders, including substance use, bipolar, and personality disorders, than in the general population. Although individuals with psychotic disorders might be expected to be more vulnerable to PBG, fewer studies have focused on this comorbidity. The aim of this review was to estimate the prevalence of PBG in people with psychotic disorders.MethodsMedline (Ovid), EMBASE, PsycINFO (Ovid), CINAHL, CENTRAL, Web of science, and ProQuest were searched on November 1, 2023, without language restrictions. Observational and experimental studies including individuals with psychotic disorders and reporting the prevalence of PBG were included. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal for systematic reviews of prevalence data. The pooled prevalence of PBG was calculated using a fixed effects generalized linear mixed model and presented through forest plots.ResultsOf 1271 records screened, 12 studies (n = 3443) were included. The overall prevalence of PBG was 8.7% (95% CI = 7.8%–9.7%, I2 = 69%). A lower prevalence was found in studies with a low risk of bias (5.6%; 95% CI = 4.4%–7.0%) compared with studies with a moderate risk of bias (10.4%; 95% CI = 9.2%–11.7%). Different methods used to assess PBG also contributed to the heterogeneity found.ConclusionThis meta‐analysis found substantial heterogeneity, partly due to the risk of bias of the included studies and a lack of uniformity in PBG assessment. Although more research is needed to identify those at increased risk for PBG, its relatively high prevalence warrants routine screening for gambling in clinical practice.

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Impact of gaming disorder on first episode psychosis patients' evolution: Protocol for a multicentered prospective study

Huot‐Lavoie,

Desmeules,

Corbeil

et al. 2023

Early Intervention Psych

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AimsThe objective of this study is to underline the impact of Gaming Disorder on the clinical evolution of patients with First Episode Psychosis. The specific aims of the study are to determine the prevalence of gaming disorder among those patients and assess the consequences of gaming on their clinical trajectory.MethodsThis is a prospective multicenter cohort study that will enrol 800 patients diagnosed with a first episode psychosis, with a follow‐up period of up to 3 years. Using a systematic screening procedure for gaming disorder, the clinical staff will assess patients gaming habits at admission and every 6 months thereafter. Information from patients' medical records will also be extracted using the same timeframe.ResultsThe patients' characteristics at admission and during follow‐up will be presented in the form of descriptive statistics and compared between different subgroups of patients using uni‐ and multivariate logistic regression models. Repeated measures ANCOVA will also be performed to analyse the impact of gaming disorders on patients' clinical path as assessed by the Positive and Negative Syndrome Scale and the Clinical Global Impression scale, considering covariates such as psychiatric diagnosis, pharmacological treatment, age, sex/gender, and duration of untreated psychosis.ConclusionThese findings will guide the development of prevention, detection, and treatment strategies for the comorbidity between gaming disorder and first episode psychosis, ultimately improving the patients' recovery.

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Détecter et traiter les troubles comorbides aux premiers épisodes psychotiques : un levier pour le rétablissement

Cited by 4 publications

References 41 publications

A Narrative Review Exploring Attention Deficit/Hyperactivity Disorder in Patients with Early Psychosis

A Narrative Review Exploring Attention Deficit/Hyperactivity Disorder in Patients with Early Psychosis

Problem gambling in psychotic disorders: A systematic review and meta‐analysis of prevalence

Impact of gaming disorder on first episode psychosis patients' evolution: Protocol for a multicentered prospective study

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