Detectability of Breast Tumor by a Hand-held Impulse-Radar Detector: Performance Evaluation and Pilot Clinical Study

Song, Hang; Sasada, Shinsuke; Kadoya, Takayuki; Okada, Morihito; Arihiro, Koji; Xiao, Xia; Kikkawa, Takamaro

doi:10.1038/s41598-017-16617-6

Cited by 93 publications

(66 citation statements)

References 46 publications

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“…As Asian women have denser breast parenchyma than their European counterparts, these results will be essential in assessing the clinical utility of microwave imaging in dense breasts. Also, in 2017, a group from Hiroshima University, Japan, described early results of a handheld, radar-based system [73]. This study included five patients, all of whom had either IDC or DCIS.…”

Section: Microwave Breast Imaging (Mbi)mentioning

confidence: 99%

Breast Cancer Detection—A Synopsis of Conventional Modalities and the Potential Role of Microwave Imaging

et al. 2020

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Global statistics have demonstrated that breast cancer is the most frequently diagnosed invasive cancer and the leading cause of cancer death among female patients. Survival following a diagnosis of breast cancer is grossly determined by the stage of the disease at the time of initial diagnosis, highlighting the importance of early detection. Improving early diagnosis will require a multi-faceted approach to optimizing the use of currently available imaging modalities and investigating new methods of detection. The application of microwave technologies in medical diagnostics is an emerging field of research, with breast cancer detection seeing the most significant progress in the last twenty years. In this review, the application of current conventional imaging modalities is discussed, and recurrent shortcomings highlighted. Microwave imaging is rapid and inexpensive. If the preliminary results of its diagnostic capacity are substantiated, microwave technology may offer a non-ionizing, non-invasive, and painless adjunct or stand-alone modality that could possibly be implemented in routine diagnostic breast care. Author Contributions: Conceptualization, B.M.M., D.O.'L, S.A.E., and M.J.K.; writing-original draft preparation, B.M.M., D.O.'L and S.A.E., writing-review and editing, B.M.M., D.O.'L, S.A.E., and M.J.K.; supervision, M.J.K.; funding acquisition, M.J.K.; All authors have read and agreed to the published version of the manuscript.

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Section: Microwave Breast Imaging (Mbi)mentioning

confidence: 99%

Breast Cancer Detection—A Synopsis of Conventional Modalities and the Potential Role of Microwave Imaging

et al. 2020

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“…In the previous study, 43 the effect of EM wave on human body is investigated using the same antenna in simulation. It was found that with the same antenna, the calculated specific absorption rate (SAR) on the average mass of 1 g are from 0.0118 to 0.0246 W/kg across the UWB band.…”

Section: Realistic Phantommentioning

confidence: 99%

Optimal microwave breast imaging using quality metrics and simulated annealing algorithm

Xiao

Liu

Song

et al. 2020

Int J RF Microw Comput Aided Eng

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Microwave breast imaging exploits dielectric contrasts between cancerous and healthy tissues at microwave frequencies to detect breast tumors. The estimation of breast optimal effective dielectric properties has a significant influence on the image quality. Recently, a novel method based on focal quality metrics (FQMs) has been proposed to investigate the patient‐specific effective dielectric properties. Although FQMs can be used to estimate the effective permittivity, the small increment of permittivity during the imaging process may lead to large computational resource consumption. In this article, an optimized microwave breast imaging method is proposed. In this method, a hybrid image quality metric is put forward which mixes the signal‐to‐clutter ratio (SCR) and focal quality metric. In addition, the simulated annealing algorithm is incorporated to facilitate image reconstruction. Experimental results demonstrate that using the proposed method, SCR is improved by 0.2 dB and tumor location error is reduced by 3.5 mm in realistic breast phantom.

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“…Examples are pre-hospital assessment, preventive screening, or long term monitoring following a medical procedure. MWI has been researched especially for stroke imaging [6], [7] and breast cancer imaging [8]- [10]. A different field in which radar and MWI techniques may prove successful, is monitoring of the cardiovascular system inside the body.…”

Section: Introductionmentioning

confidence: 99%

Coherent UWB Radar-on-Chip for In-Body Measurement of Cardiovascular Dynamics

Lauteslager

Tømmer

Lande

et al. 2019

IEEE Trans. Biomed. Circuits Syst.

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Coherent ultra-wideband (UWB) radar-on-chip technology shows great promise for developing portable and low-cost medical imaging and monitoring devices. Particularly monitoring the mechanical functioning of the cardiovascular system is of interest, due to the ability of radar systems to track sub-mm motion inside the body at a high speed. For imaging applications, UWB radar systems are required, but there are still significant challenges with in-body sensing using lowpower microwave equipment and wideband signals. Recently it was shown for the first time, on a single subject, that the arterial pulse wave can be measured at various locations in the body, using coherent UWB radar-on-chip technology. The current work provides more substantial evidence, in the form of new measurements and improved methods, to demonstrate that cardiovascular dynamics can be measured using radar-on-chip. Results across four participants were found to be robust and repeatable. Cardiovascular signals were recorded using radaron-chip systems and electrocardiography (ECG). Through ECGaligned averaging, the arterial pulse wave could be measured at a number of locations in the body. Pulse arrival time could be determined with high precision, and blood pressure pulse wave propagation through different arteries was demonstrated. In addition, cardiac dynamics were measured from the chest. This work serves as a first step in developing a portable and low-cost device for long-term monitoring of the cardiovascular system, and provides the fundamentals necessary for developing UWB radar-on-chip imaging systems.

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Detectability of Breast Tumor by a Hand-held Impulse-Radar Detector: Performance Evaluation and Pilot Clinical Study

Cited by 93 publications

References 46 publications

Breast Cancer Detection—A Synopsis of Conventional Modalities and the Potential Role of Microwave Imaging

Breast Cancer Detection—A Synopsis of Conventional Modalities and the Potential Role of Microwave Imaging

Optimal microwave breast imaging using quality metrics and simulated annealing algorithm

Coherent UWB Radar-on-Chip for In-Body Measurement of Cardiovascular Dynamics

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