Detecção de sífilis por ensaios de ELISA e VDRL em doadores de sangue do Hemonúcleo de Guarapuava, Estado do Paraná

Abstract

O objetivo desse estudo foi avaliar a soroprevalência de sífilis em 5.752 doadores de sangue atendidos no Hemonúcleo de Guarapuava-PR, em 2006. As taxas de positividade foram de 2,1% pelo teste de ensaio imunoenzimático e 0,2% pelo Veneral Disease Research Laboratory, mostrando baixa prevalência de sífilis nos indivíduos que procuraram este banco de sangue.

Blood discard rate and the prevalence of infectious and contagious diseases in blood donors from provincial towns of the state of Paraná, Brazil

“…Similar results were found in towns of the same state; Cruz Alta (16) and Santa Maria (17) with prevalences of 0.3% and 0.48%, respectively. The positivity rate for the pathology in Guarapuava, Paraná (18) according to the immune enzyme test was 2.1%, thus a higher rate than that reported in the current study. Research in blood centers of other states also showed a high positivity rate for syphilis tests, such as those in the Brazilian states of Amazonas (19) , São Paulo (7) and Sergipe (20) .…”

Syphilis seroprevalence estimates of Santa Catarina blood donors in 2010

“…Furthermore, the statistical treatment of the non-responders to follow-up testing and of the independent variables (e.g., unknown residence and education level) in the multinomial regression analysis reduced the potential bias by providing estimates of the likely relative risk in these subgroups using a Poisson regression. The sociodemographic profi le of the present study is similar to other such profi les found in the Brazilian literature, reinforcing the validity of these results and allowing generalization to other areas of the country with similar profi les 8,11,15,22,27 . Additionally, this study provides useful elements for assessing the risk of syphilis transmission by blood transfusion and for improving hemovigilance.…”

“…A similar result was noted in the neighboring State of Parana, which reported a 0.2% prevalence in VDRL reactive donors 11 . However, the largest blood bank in the State of São Paulo had a 1.7% prevalence in 2007 6 .…”

“…In Germany, the syphilis prevalence from 2008 to 2010 ranged from 31.0-42.1/100,000 donations and also increased during those years 10 . In Brazil, there is a wide variation in the reported syphilis prevalence, such as 2.1% and 0.2% prevalences in Guarapuava (Paraná), a 0.49% prevalence in Amazonas, a 0.3% prevalence in Cruz Alta (Rio Grande do Sul) and a 1.1% prevalence in São Paulo 8,[11][12][13] .…”

Prevalence of serological inability of blood donors in regional blood center of Montes Claros, Minas Gerais Prevalência de inaptidão sorológica dos doadores de sangue no hemocentro regional de Montes Claros, Minas Gerais

“…In some countries, like Brazil, it is considered one of the major public health problems, similar to other emerging infectious diseases in the country. 20 According to the World Health Organization, it is estimated about 12 million new cases of people infected each year with some disease related to sex, among which syphilis has great representation. 21 Currently, the search for syphilis is done with specific and non-specific tests, and most laboratories have opted for Venereal Disease Research Laboratory (VDRL) and enzyme-linked immunosorbent assay (ELISA) for being easy to perform.…”