Destructive Lesions of the Spine in Rheumatoid Ankylosing Spondylitis

Kanefield, Donald G.; Mullins, Brandon P; Freehafer, Alvin A.; Furey, J. George; Horenstein, Simon; Chamberlin, William B.

doi:10.2106/00004623-196951070-00015

Cited by 46 publications

(15 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…There is no agreement about the origin of these lesions, some authors favouring traumatic (Kanefield et al, 1969;Rivelis and Freiberger, 1969;Cawley et al, 1972;Gougeon et al, 1977), others inflammatory mechanisms (Romanus and Yden 1952;Coste et al, 1963;Little et al, 1974 (Gofton, 1968) 9 subjects (14%) had radiological signs of SD. These 9 patients, together with their available first-degree relatives (>16 years of age)-2 parents, 3 sibs, and 3 children-underwent clinical and radiological investigation.…”

mentioning

confidence: 99%

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications.

Modena¹,

Migone²,

Daneo³

et al. 1978

Annals of the Rheumatic Diseases

View full text Add to dashboard Cite

SUMMARY Nine cases from among 64 patients with ankylosing spondylitis (AS) are described. In addition to bilateral sacroiliitis these cases had a peculiar type of spondylodiscitis characterised by quite diffuse and marked sclerosis of multiple vertebral bodies, with only minimal erosions of the adjacent vertebral plates while classical syndesmophytosis was absent. The antigen HLA-B27 was found only in 1 of these 9 cases. This type of spondylodiscitis could discriminate among all the patients with AS a subgroup with a peculiar clinical pattern and a probably distinctive pathological mechanism.

show abstract

mentioning

confidence: 99%

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications.

Modena¹,

Migone²,

Daneo³

et al. 1978

Annals of the Rheumatic Diseases

View full text Add to dashboard Cite

show abstract

“…6 Histological descriptions may vary, 7 but generally the lesion is composed of necrotic bone and granulation tissue compatible with pseudoarthrosis. 8,9 Some reports support the theory that these lesion are traumatic in origin, 5,8,10 and some support an atraumatic origin. 11,12 When these lesions occur in the earlier phase of the disease, they are similar in appearance to those of bacterial discitis, as mentioned above, and they are very difficult to differentiate using only radiographs.…”

Section: Discussionmentioning

confidence: 92%

Discovertebral lesion in ankylosing spondylitis: differential diagnosis with discitis by magnetic resonance imaging

Tsuchiya

Nagamine

Iwamoto

2002

Modern Rheumatology

View full text Add to dashboard Cite

Ankylosing spondylitis (AS) is occasionally accompanied by erosive changes in the vertebral endplate at one or more restricted levels (Andersson lesions). The radiographic findings of this lesion are similar to those of bacterial discitis, and a differential diagnosis between them is often difficult. These diseases must be diagnosed correctly because they require different treatments. In order to evaluate the prevalence of Andersson lesions in the Japanese population, we examined 31 cases of AS which were treated in our department, and Andersson lesions were found in three (9.7%) of them. All these three cases developed Andersson lesions in the earlier phase of the AS, and differentiating the lesions from bacterial discitis was difficult. The details of these three cases are reviewed, and the importance of differentiating between Andersson lesions and bacterial discitis is discussed. Plain radiographs showed no clear difference between these conditions, but magnetic resonance imaging (MRI) was found to be more efficient.

show abstract

“…Furthermore, the ankylosed spine is prone to fracture after minor trauma due to these changes in its biomechanical properties, and the risk of spinal compression fractures in such cases may be 7-fold that of healthy individuals 3) . Normal bones are strong, yet light and flexible, and resistant to fracture, but because of the brittle nature of the spine in AS, stress fractures can develop after minor trauma or even in the absence of a specific trauma history 2,8,14) . The precise cause of the neural arch stress fracture in our patient was not established.…”

Section: Discussionmentioning

confidence: 99%

Bilateral Pedicle Stress Fracture Accompanying Spondylolysis in a Patient with Ankylosing Spondylitis

Kim

2010

J Korean Neurosurg Soc

View full text Add to dashboard Cite

J Korean Neurosurg Soc 48 : [70][71][72] 2010 Bilateral pedicle stress fracture is a rare entity and few cases have been reported in the literature. Furthermore, the majority of these reports concern previous spine surgery or stress-related activities. Here, the authors report ankylosing spondylitis as a new cause of bilateral pedicle stress fractures accompanying spondylolysis. The reported case adds to the literature on bilateral pedicle stress fracture and spondylolysis by documenting that ankylosing spondylitis is another cause of this condition.

show abstract

Destructive Lesions of the Spine in Rheumatoid Ankylosing Spondylitis

Cited by 46 publications

References 0 publications

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications.

Spondylodiscitis and ankylosing spondylitis: HLA typing and nosological implications.

Discovertebral lesion in ankylosing spondylitis: differential diagnosis with discitis by magnetic resonance imaging

Bilateral Pedicle Stress Fracture Accompanying Spondylolysis in a Patient with Ankylosing Spondylitis

Contact Info

Product

Resources

About