Desmoplastic ameloblastoma – A review

Abstract

SUMMARY Among the ameloblastomas, the desmoplastic variation is rare. The desmoplastic ameloblastoma (DA) is characterized by specific clinical, imaging, and histological features. The here presented retrospective analysis investigated the clinicoradiographic features of an overall of 115 DA-cases, having been reported in literature from 1984 to 2008. DA showed a nearly equal male to female ratio (55/59) with a prevalence within the forth and fifth decades. Sixty-two lesions occurred in the mandible and fifty-one lesions in the maxilla. Clinically, a painless swelling with buccal extension was the most common presentation being found in 48 cases. Radiologically, the lesion often presented multilocular (49.3%; 36/73), mixed radiolucent/radiopaque (55.6%; 50/90) and with ill-defined borders (64.0%; 48/75). Whereas enucleation provided a recurrence rate of 21.1%, resection reduced this rate remarkably to 3.1%. The average period until recurrence was 36.9 months. Histologically, scattered epithelial nests and extensively desmoplasia were prominent features of DA. In conclusion, these retrospective results confirm the statement that DA is a variation among ameloblastomas. DA present clinicoradiographic and histologic distinct features, when compared with “conventional ameloblastomas”.

Intraosseous mucoepidermoid carcinoma: a review of the diagnostic imaging features of four jaw cases

“…[30][31][32][33][34] However, the well-defined periphery of ameloblastoma is commonly uniformly thin and corticated, unlike the findings of this review of IMC and the case reported by Raut and Khedkar, 22 of an uneven, thick, sclerotic a b Figure 1 (a) Axial and (b) coronal. CT bone windows of Case 1 show the epicentre of the lesion at the root apex in the right maxillary alveolar process.…”

“…Another consistent radiographic feature of IMC in this study, also noted in the case series by Johnson and Velez, 16 is the presence of internal foci of amorphous sclerotic bone, a finding not typical of solid, multicystic ameloblastoma. [30][31][32][33][34] However, the desmoplastic variant of ameloblastoma and cases of recurrent conventional ameloblastoma have been documented to contain a similar radiographic internal structure to IMC, 30,34 and may prove difficult, if not impossible, to distinguish from IMC ( Figure 5). The typical behaviour of the IMC seen in this review is to break through the outer cortex of the jaw and extend into surrounding soft tissue.…”

A case report of desmoplastic ameloblastoma

“…However, a well-defined radiolucent lesion may occur in a similar manner to that reported by Reichart et al (11), where 51% of the tumors were described as unilocular. Nevertheless, the DA frequently appears as a poorly defined, mixed, radiolucent-radiopaque lesion mimicking a benign fibro-osseous lesion, especially when evaluating panoramic and periapical radiographs (2,7,12). Through the CBCT, however, it is possible to verify the tomographic limits of the DA.…”

“…DA is a tumor with specific clinical, image, and histological features. In additional, DA is a rare form of tumor and has been described in 115 cases in English literature (2). Radiographically, 50% of DA shows an image suggesting a benign fibro-osseous lesion (2,3).…”

“…In additional, DA is a rare form of tumor and has been described in 115 cases in English literature (2). Radiographically, 50% of DA shows an image suggesting a benign fibro-osseous lesion (2,3). Eventually, the clinical-radiographic features of DA may be ignored by surgeons and radiologists who more easily recognized the solid/multicystic variant of the ameloblastoma.…”