Desmoid fibromatosis of the pancreas––A case report with radiologic-pathologic correlation

Khanna, Kanika; Mofakham, Fatemeh Abdollahi; Gandhi, Darshan; Jain, Nitin B.

doi:10.1016/j.radcr.2020.08.061

Cited by 8 publications

(3 citation statements)

References 13 publications

(17 reference statements)

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“…A DTF is a locally aggressive fibroblastic proliferation that is characterized by a variable and sometimes unpredictable clinical course [6] . In some instances, the lesions remain stable for long periods with no intervention, while in other cases, the lesions grow rapidly [7] .…”

Section: Discussionmentioning

confidence: 99%

A desmoid-type fibromatosis in the retroperitoneum of the gastro-pancreatic region that was resected with a distal pancreatomy: a case report

Imagami

Togawa

et al. 2022

Radiology Case Reports

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Section: Discussionmentioning

confidence: 99%

A desmoid-type fibromatosis in the retroperitoneum of the gastro-pancreatic region that was resected with a distal pancreatomy: a case report

Imagami

Togawa

et al. 2022

Radiology Case Reports

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“…In solid pancreatic pseudopapillary tumor, weak early arterial enhancement and gradual increase in the portal-venous phase was characteristic manifestation[ 20 ]. Local invasion to adjacent vasculature causing pseudoaneurysms may also be observed in many pancreatic adenocarcinoma cases[ 21 ]. Our case is unique in that there werefew symptoms of the primary tumor, and paratesticular nodules werethe only first sign of metastasis and pancreatic cancer.…”

Section: Discussionmentioning

confidence: 99%

“…Immunohistochemistry is currently considered the most sensitive and specific method to determine the origin of the tumor. Singh et al [ 22 ] reported a case of duodenum bleeding due to metastatic endometrial adenocarcinoma which was confirmed by histology and positive cytokeratin 7, vimentin, and paired box gene 8 in immunohistochemistry[ 21 ]. In our case, mesothelioma was excluded due to thenegative expression of calretinin, MC, and WT-1.…”

Section: Discussionmentioning

confidence: 99%

Tunica vaginalis testis metastasis as the first clinical manifestation of pancreatic adenocarcinoma: A case report

Zhang¹,

Ma²,

Gao³

et al. 2021

WJCC

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BACKGROUND Metastases from pancreas or ampullary malignancies are common, but the spread to testicle and paratesticular tissue is exceedingly rare. To the best of our knowledge, fewer than 30 cases have been reported in the literature. More rarely, metastasis to tunica vaginalis testis occurs without involvement of the testes and epididymis. CASE SUMMARY A 65-year-old male who complained of painless swelling of the left scrotum for over 1 wk was referred to the Department of Urology. Scrotal ultrasound showed left testicular hydrocele with paratesticular masses. Chest computed tomography revealed lung metastasis and enlarged left supraclavicular lymph node.The blood tumor markersalpha-fetoprotein, human chorionic gonadotropin, and serum lactate dehydrogenase were withinnormal limits.The preoperative diagnosis was left testicular tumor with lung metastasis. Then radical orchidectomy of the left testicle and high ligation of the spermatic cord were performed, and postoperative histopathology suggested metastatic tumors that was confirmed by an abdominal computed tomographic scan. The positive computed tomography findings, in conjunction with the expression of cytokeratin 7 (CK7), CK20, CK5/6, and absence of expression of Wilms’ tumor suppressor gene 1, calretinin, melanocyte, prostate-specific antigen, thyroid transcription factor-1, GATA binding protein 3, caudal type homeobox 2, and napsinA supported the diagnosis of pancreatic adenocarcinoma. The outcome of this patient was unsatisfactory, and he died 3 mo later. CONCLUSION This case suggests that pancreatic metastatic carcinoma must be considered in the differential diagnosis of scrotal enlargement. The advanced age of the patient wassuggestive of a secondary testicular tumor.In addition, careful physical examination and ultrasonography as well as radiological examination have become a standard modality.

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Radiological features of pancreatic desmoid-type fibromatosis: a case series and systematic review

Tanishima,

Kurokawa,

Sone

et al. 2024

Abdom Radiol

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Purpose This retrospective study aimed to investigate the radiological features of pancreatic desmoid-type fibromatosis (PDF) and systematically review the previous publications and two new cases. Methods We searched PubMed, Cochrane Library, and Web of Science Core Collection and included 31 patients with pathologically proven PDFs with analyzable preoperative computed tomography (CT) and magnetic resonance imaging, including two patients from our institution and 29 patients from 28 publications. Two board-certified radiologists reviewed all images. Results The median age of the patients was 39 years, with a male dominance observed (male, 54.8% vs. female, 45.2%). Abdominal pain was the most frequent symptom, occurring in 58.1% of cases. Surgical resection was performed in all cases of PDFs, resulting in a recurrence rate of 8.3% (2/24). The tumors were most commonly located in the pancreatic tail (23/31, 74.2%). In terms of morphology, a “solid” shape was most prevalent (14/31, 45.2%), followed by a “solid and cystic” shape (9/31, 29.0%) and a “cystic” shape (8/31, 25.8%). Characteristic radiological features included heterogeneous enhancement of the solid portion of the tumors on CT scans (13/20, 65%), moderate-to-weak enhancement in the late phase on CT (16/17, 94.1%), and a presence of cystic components in the tumors (17/31, 54.8%). In 16.1% (5/31) of PDFs, the cystic component was pathologically confirmed to be a dilated pancreatic duct. Conclusion We summarized the clinical and imaging characteristics of PDF. Although the incidence may not be high, cystic components suggesting a dilated pancreatic duct within the tumor are unique imaging features in PDF.

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Desmoid fibromatosis of the pancreas––A case report with radiologic-pathologic correlation

Cited by 8 publications

References 13 publications

A desmoid-type fibromatosis in the retroperitoneum of the gastro-pancreatic region that was resected with a distal pancreatomy: a case report

A desmoid-type fibromatosis in the retroperitoneum of the gastro-pancreatic region that was resected with a distal pancreatomy: a case report

Tunica vaginalis testis metastasis as the first clinical manifestation of pancreatic adenocarcinoma: A case report

Radiological features of pancreatic desmoid-type fibromatosis: a case series and systematic review

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