Desirability Function Approach for the Optimization of Hydroalcoholic Solvent Extraction Conditions for Antioxidant Compounds from Olive Leaves
NİLÜFER VURAL,
ÖZGE ALGAN-CAVULDAK,
M. ABDÜLKADİR AKAY
Abstract:The goal of this work was to obtain a rich olive leaf extract with high antioxidant activity due to its content of oleuropein (OLE), hydroxytyrosol (HT) and other phenolics, which have a synergistic effect on total antioxidant activity (TAA).The extraction parameters in the solvent extraction were investigated using response surface methodology (RSM) to produce the best results of HT and TAA in olive leaf extracts. A Box Wilson-CCD design was applied, the multi-objective optimization (MOO) was computed with Pa… Show more
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