Designing of the centers for adsorption of bile acids on a silica surface

Belyakova, L. A.; Besarab, L. N.; Roik, N. V.; Lyashenko, D. Yu.; Власова, Н. Н.; Golovkova, L. P.; Chuĭko, A. A.

doi:10.1016/j.jcis.2005.06.081

Cited by 21 publications

(5 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Chemically modified silica with attached aminopropyl, imidazolyl, and trimethylsilyl groups, with adsorptive and coordinative grafted hemin were synthesized (47)(48)(49)(50)(51)(52)(53)(54)(55) and adsorption of some bile acids on the surface of hydroxylated silica, synthesized siliceous adsorbents and cholestyramine were investigated by Belyakova et al [215]. It was found that the main contribution to the total adsorption is caused by electrostatic attraction between anions of bile acids and positively charged sites of the surface of modified silica and also by dispersion interactions between steroid skeleton of bile acids and functional groups of modified silicon dioxides.…”

Section: Adsorption Of Biomolecules On Silica Surfacementioning

confidence: 99%

Adsorption of organic molecules on silica surface

Parida¹,

Dash²,

Patel³

et al. 2006

Advances in Colloid and Interface Science

604

360

View full text Add to dashboard Cite

Section: Adsorption Of Biomolecules On Silica Surfacementioning

confidence: 99%

Adsorption of organic molecules on silica surface

Parida¹,

Dash²,

Patel³

et al. 2006

Advances in Colloid and Interface Science

604

360

View full text Add to dashboard Cite

“…Attachment of Iron Porphyrin. The attachment was carried out by immersing amino-terminated silanized nanowire FETs into a NaOH solution (1 M) containing iron-porphyrin (10 M) for 2 h. 20 This was followed by a thorough rinse with NaOH solvent and sonication in NaOH bath for 5 min to remove physisorbed porphyrin molecules.…”

mentioning

confidence: 99%

Improving Nanowire Sensing Capability by Electrical Field Alignment of Surface Probing Molecules

et al. 2013

View full text Add to dashboard Cite

We argue that the structure ordering of self-assembled probing molecular monolayers is essential for the reliability and sensitivity of nanowire-based field-effect sensors because it can promote the efficiency for molecular interactions as well as strengthen the molecular dipole field experienced by the nanowires. In the case of monolayers, we showed that structure ordering could be improved by means of electrical field alignment. This technique was then employed to align multilayer complexes for nanowire sensing applications. The sensitivity we achieved for detection of hybridization between 15-base single-strand DNA molecules is 0.1 fM and for alcohol sensors is 0.5 ppm. The reliability was confirmed by repeated tests on chips that contain multiple nanowire sensors.

show abstract

“…Even if there are few reports about the relation of silicate directly with glycemic control, silicate has the characteristic of a bile acid-binding property to decrease serum cholesterol as a primary precursor of bile acid. 10,[25][26][27][28] Thus, we quantified the amount of bile acid in the stool of mice ingesting SW, but there was no significant difference among the 4 groups (unpublished data). Further studies will be required to elucidate the mechanism for controlling blood glucose between silicate and bile acids and to elucidate the mechanism of SW for metabolic effects.…”

Section: Discussionmentioning

confidence: 99%

High Levels of Akkermansia muciniphilia Growth Associated With Spring Water Ingestion Prevents Obesity and Hyperglycemia in a High-fat Diet-Induced Mouse Model

Kim

Sohn

Choi

et al. 2022

Natural Product Communications

View full text Add to dashboard Cite

Background: Type 2 diabetes may be alleviated by mineral water (MW) ingestion. We investigated whether spring water (SW) (a kind of mixed MW) ingestion influences metabolic parameters via alteration of the gut microbiota in high-fat diet (HFD)-fed mice. Method: We divided 32 C57/BL mice into 4 equal groups: normal diet with tap water (Control), high-fat diet with tap water (HFD), normal diet with SW (SW), and high-fat diet with SW (HFD + SW). During this experiment, we checked the body weight (BW) with fasting blood sugar (FBS) every week and all mice were sacrificed in the 17th week to observe serological markers, internal organs, and composition of gut microbiota. Results: The BW of HFD-fed mice was significantly higher than that of mice fed an HFD + SW diet in the early period of the experiment. Fasting blood glucose (FBG) in the HFD group showed a fluctuating pattern compared to the HFD + SW group, and the area under the curve (AUC) value of the oral glucose tolerance test (OGTT) was significantly greater in the HFD group than in the HFD + SW group. Serologic markers were not significantly different between the HFD and HFD + SW groups. Histologically, the most severe fatty changes in the liver were observed in the HFD group. Lastly, the gut levels of Akkermansia muciniphilia were 100-fold higher in the HFD + SW group than in the HFD mice. Conclusion: These findings indicate that SW ingestion, and the associated high levels of A muciniphilia growth in the gut, may improve the early stage of obesity and ameliorate HFD-induced hyperglycemia.

show abstract

Designing of the centers for adsorption of bile acids on a silica surface

Cited by 21 publications

References 7 publications

Adsorption of organic molecules on silica surface

Adsorption of organic molecules on silica surface

Improving Nanowire Sensing Capability by Electrical Field Alignment of Surface Probing Molecules

High Levels of Akkermansia muciniphilia Growth Associated With Spring Water Ingestion Prevents Obesity and Hyperglycemia in a High-fat Diet-Induced Mouse Model

Contact Info

Product

Resources

About