This chapter describes the findings of a research aimed to determine the cultural characteristics which have incidence on the management effectiveness of IT projects. A quantitative study was carried out. Confirmatory factor analysis (CFA) and structural equation modelling (SEM) were applied. A random sample of 139 respondents conformed by leaders and team members who developed IT projects in private companies from different economic sectors located in Bogotá, Colombia was used. The evidence shows that the adaptation to solve problems has incidence in the management effectiveness of IT projects and the compliance of stakeholder expectations can be predicted from the alignment level of the projects with the strategy and the consideration of their needs and opinions. The study extends the theory in project management and information technology. The results can guide the efforts of project offices to identify cultural characteristics which can be intervened to enhance the project success.