Designing an extended release waxy matrix tablet containing nicardipine–hydroxy propyl β cyclodextrin complex

Abstract

The prepared waxy matrix tablet containing NC complexes with CD shows promising results as extended release tablets.

Fabrication and Evaluation of Nanostructured Herbal Oil/Hydroxypropyl-β-Cyclodextrin/Polyvinylpyrrolidone Mats for Denture Stomatitis Prevention and Treatment

“…The spectrum of PVP presented peaks at 3452.2 , 2926.5, 1663.4, 1415.7, and 1290.1 cm −1 that were attributed to N-H, CH 2 , C=O, C-N stretching vibration, and C-H bending, respectively (29). The peaks at 3423.7, 2915.4, 1167.8, and 1083.7 of the HPβCD spectrum corresponded to O-H, C-H, C-H, and C-O stretching vibrations, respectively (30). The pure PVP/HPβCD nanofiber mats exhibited absorption peaks as observed in the spectra of PVP and HPβCD.…”

“…The samples of the herbal oil loaded nanofiber mats with varied oil were incubated with Candida suspensions under agitation at 37°C. After the predetermined contact times (5,15,30,60, and 120 min), small aliquots of the samples were removed, and the microorganisms were counted by spreading each sample onto an SDA agar plate. The plates were incubated for 24 h, and the viable colonies were counted.…”

Comparative FTIR, Compaction and In vitro Dissolution Studies of Plectranthus esculentus Modified Starches in Metronidazole Tablet Formulations by Direct Compression

“…Table 4. The mean yield pressure, P y , is inversely related to the formulations ability to deform plastically under pressure [21,22]. The P y values showed that MCC PH 101 has the lowest while APS exhibited the highest.…”

“…This indicates that there was no chemical interaction between the drug and excipients used. FTIR spectroscopy is an important tool used to assess the interaction between excipients and guest molecules in the solid state which can be revealed as shifts disappearances or changes in the absorption spectrum of the API [2,21].…”

Formulation and evaluation of sustain released matrix tablet of atenolol

“…Natural polymer chitosan is known for its permeability enhancement through mucosal membrane and will enhance drug absorption. This in turn will reduce the dose size and dosing frequency and subsequently will result in result in efficient drug therapy and patient compliance [13][14][15][16][17][18][19][20]…”